node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRIX1 | BYSL | ENSP00000338862 | ENSP00000230340 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family | 0.911 |
BRIX1 | C12orf10 | ENSP00000338862 | ENSP00000267103 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 | 0.896 |
BRIX1 | DPH5 | ENSP00000338862 | ENSP00000359127 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | Diphthine methyl ester synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis | 0.683 |
BRIX1 | MRPL3 | ENSP00000338862 | ENSP00000264995 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | Mitochondrial ribosomal protein L3 | 0.514 |
BRIX1 | NHP2 | ENSP00000338862 | ENSP00000274606 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | H/ACA ribonucleoprotein complex subunit 2; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse tran [...] | 0.925 |
BRIX1 | PBDC1 | ENSP00000338862 | ENSP00000362456 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | Protein PBDC1; Polysaccharide biosynthesis domain containing 1; Belongs to the PBDC1 family | 0.414 |
BRPF1 | C12orf10 | ENSP00000373340 | ENSP00000267103 | Peregrin; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Preferentially mediates histone H3-K23 acetylation. Positively regulates the transcription of RUNX1 and RUNX2; Bromodomain containing | UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 | 0.669 |
BYSL | BRIX1 | ENSP00000230340 | ENSP00000338862 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | 0.911 |
BYSL | C12orf10 | ENSP00000230340 | ENSP00000267103 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family | UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 | 0.652 |
BYSL | DPH5 | ENSP00000230340 | ENSP00000359127 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family | Diphthine methyl ester synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis | 0.646 |
BYSL | MRPL3 | ENSP00000230340 | ENSP00000264995 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family | Mitochondrial ribosomal protein L3 | 0.626 |
BYSL | NHP2 | ENSP00000230340 | ENSP00000274606 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family | H/ACA ribonucleoprotein complex subunit 2; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse tran [...] | 0.903 |
C12orf10 | BRIX1 | ENSP00000267103 | ENSP00000338862 | UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | 0.896 |
C12orf10 | BRPF1 | ENSP00000267103 | ENSP00000373340 | UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 | Peregrin; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Preferentially mediates histone H3-K23 acetylation. Positively regulates the transcription of RUNX1 and RUNX2; Bromodomain containing | 0.669 |
C12orf10 | BYSL | ENSP00000267103 | ENSP00000230340 | UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family | 0.652 |
C12orf10 | DNAJC17 | ENSP00000267103 | ENSP00000220496 | UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 | DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription; DNAJ heat shock proteins | 0.723 |
C12orf10 | DPH5 | ENSP00000267103 | ENSP00000359127 | UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 | Diphthine methyl ester synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis | 0.608 |
C12orf10 | MFSD5 | ENSP00000267103 | ENSP00000442688 | UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 | Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily | 0.588 |
C12orf10 | MRPL3 | ENSP00000267103 | ENSP00000264995 | UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 | Mitochondrial ribosomal protein L3 | 0.642 |
C12orf10 | NHP2 | ENSP00000267103 | ENSP00000274606 | UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 | H/ACA ribonucleoprotein complex subunit 2; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse tran [...] | 0.677 |