C12orf10 protein (human) - STRING database

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C12orf10

UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10 (376 aa)

Predicted Functional Partners:

BRIX1

0.896

PBDC1

0.767

DNAJC17

0.723

NHP2

0.677

BRPF1

0.669

BYSL

0.652

MRPL3

0.642

DPH5

0.608

PFDN5

0.596

MFSD5

0.588

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRIX1	BYSL	ENSP00000338862	ENSP00000230340	Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit	Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family	0.911
BRIX1	C12orf10	ENSP00000338862	ENSP00000267103	Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit	UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10	0.896
BRIX1	DPH5	ENSP00000338862	ENSP00000359127	Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit	Diphthine methyl ester synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis	0.683
BRIX1	MRPL3	ENSP00000338862	ENSP00000264995	Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit	Mitochondrial ribosomal protein L3	0.514
BRIX1	NHP2	ENSP00000338862	ENSP00000274606	Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit	H/ACA ribonucleoprotein complex subunit 2; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse tran [...]	0.925
BRIX1	PBDC1	ENSP00000338862	ENSP00000362456	Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit	Protein PBDC1; Polysaccharide biosynthesis domain containing 1; Belongs to the PBDC1 family	0.414
BRPF1	C12orf10	ENSP00000373340	ENSP00000267103	Peregrin; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Preferentially mediates histone H3-K23 acetylation. Positively regulates the transcription of RUNX1 and RUNX2; Bromodomain containing	UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10	0.669
BYSL	BRIX1	ENSP00000230340	ENSP00000338862	Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family	Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit	0.911
BYSL	C12orf10	ENSP00000230340	ENSP00000267103	Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family	UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10	0.652
BYSL	DPH5	ENSP00000230340	ENSP00000359127	Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family	Diphthine methyl ester synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis	0.646
BYSL	MRPL3	ENSP00000230340	ENSP00000264995	Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family	Mitochondrial ribosomal protein L3	0.626
BYSL	NHP2	ENSP00000230340	ENSP00000274606	Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family	H/ACA ribonucleoprotein complex subunit 2; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse tran [...]	0.903
C12orf10	BRIX1	ENSP00000267103	ENSP00000338862	UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10	Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit	0.896
C12orf10	BRPF1	ENSP00000267103	ENSP00000373340	UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10	Peregrin; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Preferentially mediates histone H3-K23 acetylation. Positively regulates the transcription of RUNX1 and RUNX2; Bromodomain containing	0.669
C12orf10	BYSL	ENSP00000267103	ENSP00000230340	UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10	Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family	0.652
C12orf10	DNAJC17	ENSP00000267103	ENSP00000220496	UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10	DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription; DNAJ heat shock proteins	0.723
C12orf10	DPH5	ENSP00000267103	ENSP00000359127	UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10	Diphthine methyl ester synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis	0.608
C12orf10	MFSD5	ENSP00000267103	ENSP00000442688	UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10	Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily	0.588
C12orf10	MRPL3	ENSP00000267103	ENSP00000264995	UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10	Mitochondrial ribosomal protein L3	0.642
C12orf10	NHP2	ENSP00000267103	ENSP00000274606	UPF0160 protein MYG1, mitochondrial; Chromosome 12 open reading frame 10	H/ACA ribonucleoprotein complex subunit 2; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse tran [...]	0.677

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