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STRINGSTRING
LMBRD1 LMBRD1 RNF32 RNF32 LCN1 LCN1 DNAJC22 DNAJC22 SH2D3C SH2D3C LMBR1L LMBR1L IKZF4 IKZF4 FKBP10 FKBP10 RHEBL1 RHEBL1 GRIN3A GRIN3A HTR5A HTR5A
"LMBR1L" - Protein LMBR1L in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
LMBR1LProtein LMBR1L; Probable LCN1 receptor. May mediate LCN1 endocytosis (489 aa)    
Predicted Functional Partners:
LCN1
Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family (176 aa)
        
 
  0.904
LMBRD1
Probable lysosomal cobalamin transporter; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV) (540 aa)
            
  0.725
DNAJC22
DnaJ homolog subfamily C member 22; May function as a co-chaperone; DNAJ heat shock proteins (341 aa)
            
  0.722
HTR5A
5-hydroxytryptamine receptor 5A; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins; 5-hydroxytryptamine receptors, G protein-coupled (357 aa)
            
  0.688
RNF32
RING finger protein 32; May play a role in sperm formation; Ring finger proteins (362 aa)
      
   
  0.655
IKZF4
Zinc finger protein Eos; DNA-binding protein that binds to the 5’GGGAATRCC-3’ Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T- cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 (By similarity) (585 aa)
            
  0.616
FKBP10
Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis; EF-hand domain containing (582 aa)
            
  0.609
GRIN3A
Glutamate receptor ionotropic, NMDA 3A; NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. May play a role in the development of dendritic spines. May play a role in PPP2CB-NMDAR mediated signaling mechanism (By similarity) (1115 aa)
      
   
  0.590
RHEBL1
GTPase RhebL1; Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2 (183 aa)
            
  0.546
SH2D3C
SH2 domain-containing protein 3C; Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-dependent cell migration (By similarity); NSP adaptor proteins (860 aa)
      
   
  0.545
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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