RNF141 protein (human) - STRING database

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RNF141

RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins (230 aa)

Predicted Functional Partners:

RNF208

0.644

MBP

0.561

MVK

0.541

STOM

0.530

RNF41

0.497

RNF113B

0.491

RNF181

0.481

RNF32

0.477

TRIM31

0.474

TCN1

0.471

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MBP	RNF141	ENSP00000380958	ENSP00000265981	Myelin basic protein; The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non- classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T- ce [...]	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	0.561
MVK	RNF141	ENSP00000443551	ENSP00000265981	Mevalonate kinase; May be a regulatory site in cholesterol biosynthetic pathway; Belongs to the GHMP kinase family. Mevalonate kinase subfamily	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	0.541
RNF113B	RNF141	ENSP00000267291	ENSP00000265981	Ring finger protein 113B	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	0.491
RNF141	MBP	ENSP00000265981	ENSP00000380958	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	Myelin basic protein; The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non- classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T- ce [...]	0.561
RNF141	MVK	ENSP00000265981	ENSP00000443551	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	Mevalonate kinase; May be a regulatory site in cholesterol biosynthetic pathway; Belongs to the GHMP kinase family. Mevalonate kinase subfamily	0.541
RNF141	RNF113B	ENSP00000265981	ENSP00000267291	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	Ring finger protein 113B	0.491
RNF141	RNF181	ENSP00000265981	ENSP00000306906	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	E3 ubiquitin-protein ligase RNF181; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates; Belongs to the RNF181 family	0.481
RNF141	RNF208	ENSP00000265981	ENSP00000376572	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	Ring finger protein 208	0.644
RNF141	RNF32	ENSP00000265981	ENSP00000385285	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	RING finger protein 32; May play a role in sperm formation; Ring finger proteins	0.477
RNF141	RNF41	ENSP00000265981	ENSP00000342755	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	E3 ubiquitin-protein ligase NRDP1; Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins. Polyubiquitinates MYD88. Negatively regulates MYD88-dependent production of proinflammatory cytokines. Can promote TRIF-dependent production of type I interferon and inhibits infection with vesicular stomatitis virus (By similarity). Promotes also activation of TBK1 and IRF3. Involved in the ubiquitination of erythropoietin (EPO) and interleukin-3 (IL-3) receptors. Thus, through maintaining basal levels of cytokine receptors, RNF41 is involved in the control of hemat [...]	0.497
RNF141	STOM	ENSP00000265981	ENSP00000286713	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	Erythrocyte band 7 integral membrane protein; Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity; Belongs to the band 7/mec-2 family	0.530
RNF141	TCN1	ENSP00000265981	ENSP00000257264	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	Transcobalamin-1; Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach; Belongs to the eukaryotic cobalamin transport proteins family	0.471
RNF141	TRIM31	ENSP00000265981	ENSP00000365924	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	E3 ubiquitin-protein ligase TRIM31; Regulator of Src-induced anchorage independent cell growth (By similarity). May have E3 ubiquitin-protein ligase activity; Ring finger proteins	0.474
RNF181	RNF141	ENSP00000306906	ENSP00000265981	E3 ubiquitin-protein ligase RNF181; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates; Belongs to the RNF181 family	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	0.481
RNF181	RNF208	ENSP00000306906	ENSP00000376572	E3 ubiquitin-protein ligase RNF181; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates; Belongs to the RNF181 family	Ring finger protein 208	0.583
RNF208	RNF141	ENSP00000376572	ENSP00000265981	Ring finger protein 208	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	0.644
RNF208	RNF181	ENSP00000376572	ENSP00000306906	Ring finger protein 208	E3 ubiquitin-protein ligase RNF181; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates; Belongs to the RNF181 family	0.583
RNF208	RNF41	ENSP00000376572	ENSP00000342755	Ring finger protein 208	E3 ubiquitin-protein ligase NRDP1; Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins. Polyubiquitinates MYD88. Negatively regulates MYD88-dependent production of proinflammatory cytokines. Can promote TRIF-dependent production of type I interferon and inhibits infection with vesicular stomatitis virus (By similarity). Promotes also activation of TBK1 and IRF3. Involved in the ubiquitination of erythropoietin (EPO) and interleukin-3 (IL-3) receptors. Thus, through maintaining basal levels of cytokine receptors, RNF41 is involved in the control of hemat [...]	0.545
RNF32	RNF141	ENSP00000385285	ENSP00000265981	RING finger protein 32; May play a role in sperm formation; Ring finger proteins	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	0.477
RNF41	RNF141	ENSP00000342755	ENSP00000265981	E3 ubiquitin-protein ligase NRDP1; Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins. Polyubiquitinates MYD88. Negatively regulates MYD88-dependent production of proinflammatory cytokines. Can promote TRIF-dependent production of type I interferon and inhibits infection with vesicular stomatitis virus (By similarity). Promotes also activation of TBK1 and IRF3. Involved in the ubiquitination of erythropoietin (EPO) and interleukin-3 (IL-3) receptors. Thus, through maintaining basal levels of cytokine receptors, RNF41 is involved in the control of hemat [...]	RING finger protein 141; May be involved in spermatogenesis; Ring finger proteins	0.497

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