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GAL GAL OPRM1 OPRM1 NPY1R NPY1R POMC POMC NPY NPY PDYN PDYN NMU NMU GALR3 GALR3 GALR2 GALR2 GALR1 GALR1 SST SST
"GAL" - Galanin peptides in Homo sapiens
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second shell of interactors
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GALGalanin peptides; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family (123 aa)    
Predicted Functional Partners:
GALR2
Galanin receptor type 2; Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1. The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)) (387 aa)
       
  0.998
GALR1
Galanin receptor type 1; Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity; Belongs to the G-protein coupled receptor 1 family (349 aa)
       
  0.997
GALR3
Galanin receptor type 3; Receptor for the hormone galanin. Receptor for the hormone spexin-1 (368 aa)
         
  0.995
NPY
Pro-neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family (97 aa)
         
  0.988
SST
Somatostatin; Somatostatin inhibits the release of somatotropin; Endogenous ligands (116 aa)
         
  0.979
NPY1R
Neuropeptide Y receptor type 1; Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid (384 aa)
         
  0.972
PDYN
Proenkephalin-B; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity); Belongs to the opioid neuropeptide precursor family (254 aa)
         
  0.968
POMC
Pro-opiomelanocortin; Met-enkephalin- Endogenous opiate; Belongs to the POMC family (267 aa)
         
  0.962
NMU
Neuromedin-U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder; Belongs to the NmU family (174 aa)
     
 
  0.954
OPRM1
Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] (493 aa)
         
  0.952
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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