| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CALB1 | GAD1 | ENSP00000265431 | ENSP00000350928 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | 0.802 |
| CALB1 | OSGIN2 | ENSP00000265431 | ENSP00000396445 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | Oxidative stress-induced growth inhibitor 2; May be involved in meiosis or the maturation of germ cells | 0.837 |
| CALB1 | PVALB | ENSP00000265431 | ENSP00000216200 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions; EF-hand domain containing | 0.945 |
| CALB1 | RBFOX3 | ENSP00000265431 | ENSP00000463653 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | RNA binding protein fox-1 homolog 3; Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD); RNA binding motif containing | 0.781 |
| CALB1 | S100G | ENSP00000265431 | ENSP00000369547 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | S100 calcium binding protein G; Belongs to the S-100 family | 0.764 |
| CALB1 | SDF4 | ENSP00000265431 | ENSP00000353094 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | 45 kDa calcium-binding protein; May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment; Belongs to the CREC family | 0.836 |
| CALB1 | SST | ENSP00000265431 | ENSP00000287641 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | Somatostatin; Somatostatin inhibits the release of somatotropin; Endogenous ligands | 0.770 |
| CALB1 | TH | ENSP00000265431 | ENSP00000370571 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | Tyrosine 3-monooxygenase; Plays an important role in the physiology of adrenergic neurons; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family | 0.802 |
| CALB1 | TRPV5 | ENSP00000265431 | ENSP00000265310 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | Transient receptor potential cation channel subfamily V member 5; Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay (By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 hete [...] | 0.821 |
| CALB1 | TRPV6 | ENSP00000265431 | ENSP00000352358 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | Transient receptor potential cation channel subfamily V member 6; Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine. Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)- calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vi [...] | 0.832 |
| GAD1 | CALB1 | ENSP00000350928 | ENSP00000265431 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | 0.802 |
| GAD1 | PVALB | ENSP00000350928 | ENSP00000216200 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions; EF-hand domain containing | 0.901 |
| GAD1 | RBFOX3 | ENSP00000350928 | ENSP00000463653 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | RNA binding protein fox-1 homolog 3; Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD); RNA binding motif containing | 0.751 |
| GAD1 | SDF4 | ENSP00000350928 | ENSP00000353094 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | 45 kDa calcium-binding protein; May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment; Belongs to the CREC family | 0.519 |
| GAD1 | SST | ENSP00000350928 | ENSP00000287641 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | Somatostatin; Somatostatin inhibits the release of somatotropin; Endogenous ligands | 0.762 |
| GAD1 | TH | ENSP00000350928 | ENSP00000370571 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | Tyrosine 3-monooxygenase; Plays an important role in the physiology of adrenergic neurons; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family | 0.755 |
| OSGIN2 | CALB1 | ENSP00000396445 | ENSP00000265431 | Oxidative stress-induced growth inhibitor 2; May be involved in meiosis or the maturation of germ cells | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | 0.837 |
| OSGIN2 | S100G | ENSP00000396445 | ENSP00000369547 | Oxidative stress-induced growth inhibitor 2; May be involved in meiosis or the maturation of germ cells | S100 calcium binding protein G; Belongs to the S-100 family | 0.410 |
| PVALB | CALB1 | ENSP00000216200 | ENSP00000265431 | Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions; EF-hand domain containing | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | 0.945 |
| PVALB | GAD1 | ENSP00000216200 | ENSP00000350928 | Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions; EF-hand domain containing | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | 0.901 |
