• Version:
  • 11.0 [archived version]
STRINGSTRING
SFT2D2 SFT2D2 ZDHHC13 ZDHHC13 ZNF503 ZNF503 PEX2 PEX2 MRRF MRRF HRASLS HRASLS C12orf54 C12orf54 FLNC FLNC FAM84A FAM84A HRAS HRAS FAM84B FAM84B
"HRASLS" - Phospholipid-metabolizing enzyme A-C1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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HRASLSPhospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family (273 aa)    
Predicted Functional Partners:
FAM84A
Protein FAM84A; Family with sequence similarity 84 member A (292 aa)
     
   
  0.725
FAM84B
Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family (310 aa)
     
   
  0.691
C12orf54
Uncharacterized protein C12orf54; Chromosome 12 open reading frame 54 (127 aa)
           
  0.632
FLNC
Filamin-C; Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross- linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers (2725 aa)
     
   
  0.596
HRAS
GTPase HRas; Involved in the activation of Ras protein signal transduction. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family (189 aa)
           
  0.594
PEX2
Peroxisome biogenesis factor 2; Somewhat implicated in the biogenesis of peroxisomes; Belongs to the pex2/pex10/pex12 family (305 aa)
           
  0.587
ZNF503
Zinc finger protein 503; May function as a transcriptional repressor; Zinc fingers C2H2-type (646 aa)
           
  0.585
SFT2D2
Vesicle transport protein SFT2B; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (160 aa)
           
  0.553
MRRF
Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) (262 aa)
     
   
  0.541
ZDHHC13
Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport; Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily (622 aa)
           
  0.539
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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