node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C12orf54 | HRASLS | ENSP00000316898 | ENSP00000264735 | Uncharacterized protein C12orf54; Chromosome 12 open reading frame 54 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | 0.632 |
FAM84A | HRAS | ENSP00000295092 | ENSP00000407586 | Protein FAM84A; Family with sequence similarity 84 member A | GTPase HRas; Involved in the activation of Ras protein signal transduction. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family | 0.456 |
FAM84A | HRASLS | ENSP00000295092 | ENSP00000264735 | Protein FAM84A; Family with sequence similarity 84 member A | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | 0.725 |
FAM84B | HRAS | ENSP00000302578 | ENSP00000407586 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | GTPase HRas; Involved in the activation of Ras protein signal transduction. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family | 0.509 |
FAM84B | HRASLS | ENSP00000302578 | ENSP00000264735 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | 0.691 |
FLNC | HRASLS | ENSP00000327145 | ENSP00000264735 | Filamin-C; Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross- linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | 0.596 |
HRAS | FAM84A | ENSP00000407586 | ENSP00000295092 | GTPase HRas; Involved in the activation of Ras protein signal transduction. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family | Protein FAM84A; Family with sequence similarity 84 member A | 0.456 |
HRAS | FAM84B | ENSP00000407586 | ENSP00000302578 | GTPase HRas; Involved in the activation of Ras protein signal transduction. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | 0.509 |
HRAS | HRASLS | ENSP00000407586 | ENSP00000264735 | GTPase HRas; Involved in the activation of Ras protein signal transduction. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | 0.594 |
HRASLS | C12orf54 | ENSP00000264735 | ENSP00000316898 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | Uncharacterized protein C12orf54; Chromosome 12 open reading frame 54 | 0.632 |
HRASLS | FAM84A | ENSP00000264735 | ENSP00000295092 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | Protein FAM84A; Family with sequence similarity 84 member A | 0.725 |
HRASLS | FAM84B | ENSP00000264735 | ENSP00000302578 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | 0.691 |
HRASLS | FLNC | ENSP00000264735 | ENSP00000327145 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | Filamin-C; Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross- linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers | 0.596 |
HRASLS | HRAS | ENSP00000264735 | ENSP00000407586 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | GTPase HRas; Involved in the activation of Ras protein signal transduction. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family | 0.594 |
HRASLS | MRRF | ENSP00000264735 | ENSP00000343867 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) | 0.541 |
HRASLS | PEX2 | ENSP00000264735 | ENSP00000349543 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | Peroxisome biogenesis factor 2; Somewhat implicated in the biogenesis of peroxisomes; Belongs to the pex2/pex10/pex12 family | 0.587 |
HRASLS | SFT2D2 | ENSP00000264735 | ENSP00000271375 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | Vesicle transport protein SFT2B; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex | 0.553 |
HRASLS | ZDHHC13 | ENSP00000264735 | ENSP00000400113 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport; Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily | 0.539 |
HRASLS | ZNF503 | ENSP00000264735 | ENSP00000361602 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | Zinc finger protein 503; May function as a transcriptional repressor; Zinc fingers C2H2-type | 0.585 |
MRRF | HRASLS | ENSP00000343867 | ENSP00000264735 | Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | 0.541 |