node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARL5B | C2orf42 | ENSP00000366487 | ENSP00000264434 | ADP-ribosylation factor-like protein 5B; Binds and exchanges GTP and GDP; ARF GTPase family | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | 0.521 |
BLOC1S2 | C2orf42 | ENSP00000359398 | ENSP00000264434 | Biogenesis of lysosome-related organelles complex 1 subunit 2; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (By similarity). As part of the BORC complex may play a role in l [...] | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | 0.400 |
C2orf42 | ARL5B | ENSP00000264434 | ENSP00000366487 | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | ADP-ribosylation factor-like protein 5B; Binds and exchanges GTP and GDP; ARF GTPase family | 0.521 |
C2orf42 | BLOC1S2 | ENSP00000264434 | ENSP00000359398 | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | Biogenesis of lysosome-related organelles complex 1 subunit 2; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (By similarity). As part of the BORC complex may play a role in l [...] | 0.400 |
C2orf42 | GCNT3 | ENSP00000264434 | ENSP00000379377 | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development | 0.441 |
C2orf42 | GPR50 | ENSP00000264434 | ENSP00000218316 | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | Melatonin-related receptor; Does not bind melatonin; G protein-coupled receptors, Class A orphans | 0.545 |
C2orf42 | STARD13 | ENSP00000264434 | ENSP00000338785 | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | StAR-related lipid transfer protein 13; GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells | 0.660 |
C2orf42 | TXNL4B | ENSP00000264434 | ENSP00000268483 | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | Thioredoxin-like protein 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition; Belongs to the DIM1 family | 0.482 |
C2orf42 | UBALD2 | ENSP00000264434 | ENSP00000331298 | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | UBA-like domain-containing protein 2; UBA like domain containing 2; Belongs to the UBALD family | 0.472 |
GCNT3 | C2orf42 | ENSP00000379377 | ENSP00000264434 | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | 0.441 |
GPR50 | C2orf42 | ENSP00000218316 | ENSP00000264434 | Melatonin-related receptor; Does not bind melatonin; G protein-coupled receptors, Class A orphans | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | 0.545 |
STARD13 | C2orf42 | ENSP00000338785 | ENSP00000264434 | StAR-related lipid transfer protein 13; GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | 0.660 |
TXNL4B | C2orf42 | ENSP00000268483 | ENSP00000264434 | Thioredoxin-like protein 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition; Belongs to the DIM1 family | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | 0.482 |
UBALD2 | C2orf42 | ENSP00000331298 | ENSP00000264434 | UBA-like domain-containing protein 2; UBA like domain containing 2; Belongs to the UBALD family | Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 | 0.472 |