• Version:
  • 11.0 [archived version]
STRINGSTRING
TXNL4B TXNL4B GCNT3 GCNT3 ARL5B ARL5B GPR50 GPR50 C2orf42 C2orf42 UBALD2 UBALD2 STARD13 STARD13 BLOC1S2 BLOC1S2
"C2orf42" - Uncharacterized protein C2orf42 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C2orf42Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42 (574 aa)    
Predicted Functional Partners:
STARD13
StAR-related lipid transfer protein 13; GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells (1113 aa)
           
  0.660
GPR50
Melatonin-related receptor; Does not bind melatonin; G protein-coupled receptors, Class A orphans (617 aa)
           
  0.545
ARL5B
ADP-ribosylation factor-like protein 5B; Binds and exchanges GTP and GDP; ARF GTPase family (179 aa)
           
  0.521
TXNL4B
Thioredoxin-like protein 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition; Belongs to the DIM1 family (149 aa)
           
  0.482
UBALD2
UBA-like domain-containing protein 2; UBA like domain containing 2; Belongs to the UBALD family (164 aa)
           
  0.472
GCNT3
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development (438 aa)
           
  0.441
BLOC1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (By similarity). As part of the BORC complex may play a role in l [...] (142 aa)
           
  0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]