| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AURKAIP1 | DAP3 | ENSP00000342676 | ENSP00000357320 | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | 0.992 |
| AURKAIP1 | ERAL1 | ENSP00000342676 | ENSP00000254928 | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3’ terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly | 0.924 |
| AURKAIP1 | MALSU1 | ENSP00000342676 | ENSP00000419370 | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | Mitochondrial assembly of ribosomal large subunit protein 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome; Belongs to the Iojap/RsfS family | 0.580 |
| AURKAIP1 | MRPS15 | ENSP00000342676 | ENSP00000362208 | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family | 0.983 |
| AURKAIP1 | MRPS27 | ENSP00000342676 | ENSP00000426941 | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | 28S ribosomal protein S27, mitochondrial; RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth | 0.980 |
| AURKAIP1 | NOA1 | ENSP00000342676 | ENSP00000264230 | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | Nitric oxide-associated protein 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP; Belongs to the TRAFAC class YlqF/YawG GTPase family. NOA1 subfamily | 0.770 |
| AURKAIP1 | NSUN4 | ENSP00000342676 | ENSP00000419740 | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | 5-methylcytosine rRNA methyltransferase NSUN4; Involved in mitochondrial ribosome assembly. 5- methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4; [...] | 0.499 |
| DAP3 | AURKAIP1 | ENSP00000357320 | ENSP00000342676 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | 0.992 |
| DAP3 | ERAL1 | ENSP00000357320 | ENSP00000254928 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3’ terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly | 0.960 |
| DAP3 | MALSU1 | ENSP00000357320 | ENSP00000419370 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | Mitochondrial assembly of ribosomal large subunit protein 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome; Belongs to the Iojap/RsfS family | 0.673 |
| DAP3 | MRPS15 | ENSP00000357320 | ENSP00000362208 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family | 0.999 |
| DAP3 | MRPS27 | ENSP00000357320 | ENSP00000426941 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | 28S ribosomal protein S27, mitochondrial; RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth | 0.992 |
| DAP3 | MTG2 | ENSP00000357320 | ENSP00000359859 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | Mitochondrial ribosome-associated GTPase 2; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays GTPase activity. Involved in the ribosome maturation process | 0.465 |
| DAP3 | NOA1 | ENSP00000357320 | ENSP00000264230 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | Nitric oxide-associated protein 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP; Belongs to the TRAFAC class YlqF/YawG GTPase family. NOA1 subfamily | 0.766 |
| DAP3 | TRMT10B | ENSP00000357320 | ENSP00000297994 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | tRNA methyltransferase 10 homolog B; S-adenosyl-L-methionine-dependent guanine N(1)- methyltransferase that catalyzes the formation of N(1)- methylguanine at position 9 (m1G9) in tRNAs. Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs; SPOUT methyltransferase domain containing | 0.609 |
| ERAL1 | AURKAIP1 | ENSP00000254928 | ENSP00000342676 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3’ terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | 0.924 |
| ERAL1 | DAP3 | ENSP00000254928 | ENSP00000357320 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3’ terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | 0.960 |
| ERAL1 | MALSU1 | ENSP00000254928 | ENSP00000419370 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3’ terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly | Mitochondrial assembly of ribosomal large subunit protein 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome; Belongs to the Iojap/RsfS family | 0.680 |
| ERAL1 | MRPS15 | ENSP00000254928 | ENSP00000362208 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3’ terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly | Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family | 0.920 |
| ERAL1 | MRPS27 | ENSP00000254928 | ENSP00000426941 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3’ terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly | 28S ribosomal protein S27, mitochondrial; RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth | 0.940 |
