GPR108 protein (human) - STRING database

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GPR108

G protein-coupled receptor 108; 7TM orphan receptors (543 aa)

Predicted Functional Partners:

GPR137

0.662

GPR137C

0.661

CAPNS1

0.642

TTC16

0.596

GPR137B

0.594

GPR157

0.586

TPRA1

0.581

OR12D2

0.558

RNF40

0.535

SCFD1

0.515

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAPNS1	GPR108	ENSP00000246533	ENSP00000264080	Calpain small subunit 1; Regulatory subunit of the calcium-regulated non- lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction; EF-hand domain containing	G protein-coupled receptor 108; 7TM orphan receptors	0.642
GPR108	CAPNS1	ENSP00000264080	ENSP00000246533	G protein-coupled receptor 108; 7TM orphan receptors	Calpain small subunit 1; Regulatory subunit of the calcium-regulated non- lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction; EF-hand domain containing	0.642
GPR108	GPR137	ENSP00000264080	ENSP00000411827	G protein-coupled receptor 108; 7TM orphan receptors	Integral membrane protein GPR137; G protein-coupled receptor 137; Belongs to the GPR137 family	0.662
GPR108	GPR137B	ENSP00000264080	ENSP00000355551	G protein-coupled receptor 108; 7TM orphan receptors	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	0.594
GPR108	GPR137C	ENSP00000264080	ENSP00000315106	G protein-coupled receptor 108; 7TM orphan receptors	Integral membrane protein GPR137C; G protein-coupled receptor 137C	0.661
GPR108	GPR157	ENSP00000264080	ENSP00000366628	G protein-coupled receptor 108; 7TM orphan receptors	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	0.586
GPR108	OR12D2	ENSP00000264080	ENSP00000373047	G protein-coupled receptor 108; 7TM orphan receptors	Olfactory receptor 12D2; Odorant receptor; Olfactory receptors, family 12	0.558
GPR108	RNF40	ENSP00000264080	ENSP00000325677	G protein-coupled receptor 108; 7TM orphan receptors	E3 ubiquitin-protein ligase BRE1B; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of ’Lys-120’ of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 ’Lys-4’ and ’Lys-79’ methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradic [...]	0.535
GPR108	SCFD1	ENSP00000264080	ENSP00000390783	G protein-coupled receptor 108; 7TM orphan receptors	Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity)	0.515
GPR108	TPRA1	ENSP00000264080	ENSP00000347748	G protein-coupled receptor 108; 7TM orphan receptors	Transmembrane protein adipocyte associated 1; 7TM orphan receptors	0.581
GPR108	TTC16	ENSP00000264080	ENSP00000362386	G protein-coupled receptor 108; 7TM orphan receptors	Tetratricopeptide repeat domain containing	0.596
GPR137	GPR108	ENSP00000411827	ENSP00000264080	Integral membrane protein GPR137; G protein-coupled receptor 137; Belongs to the GPR137 family	G protein-coupled receptor 108; 7TM orphan receptors	0.662
GPR137	GPR157	ENSP00000411827	ENSP00000366628	Integral membrane protein GPR137; G protein-coupled receptor 137; Belongs to the GPR137 family	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	0.447
GPR137	TPRA1	ENSP00000411827	ENSP00000347748	Integral membrane protein GPR137; G protein-coupled receptor 137; Belongs to the GPR137 family	Transmembrane protein adipocyte associated 1; 7TM orphan receptors	0.438
GPR137B	GPR108	ENSP00000355551	ENSP00000264080	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	G protein-coupled receptor 108; 7TM orphan receptors	0.594
GPR137B	GPR157	ENSP00000355551	ENSP00000366628	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	0.503
GPR137B	TPRA1	ENSP00000355551	ENSP00000347748	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	Transmembrane protein adipocyte associated 1; 7TM orphan receptors	0.428
GPR137C	GPR108	ENSP00000315106	ENSP00000264080	Integral membrane protein GPR137C; G protein-coupled receptor 137C	G protein-coupled receptor 108; 7TM orphan receptors	0.661
GPR137C	GPR157	ENSP00000315106	ENSP00000366628	Integral membrane protein GPR137C; G protein-coupled receptor 137C	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	0.766
GPR137C	TPRA1	ENSP00000315106	ENSP00000347748	Integral membrane protein GPR137C; G protein-coupled receptor 137C	Transmembrane protein adipocyte associated 1; 7TM orphan receptors	0.420

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