node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMN1 | EFHD1 | ENSP00000281471 | ENSP00000264059 | Protein AMN1 homolog; Antagonist of mitotic exit network 1 homolog | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | 0.544 |
AMN1 | TLK2 | ENSP00000281471 | ENSP00000316512 | Protein AMN1 homolog; Antagonist of mitotic exit network 1 homolog | Serine/threonine-protein kinase tousled-like 2; Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly. Negative regulator of amino acid starvation-induced autophagy | 0.719 |
EFHD1 | AMN1 | ENSP00000264059 | ENSP00000281471 | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | Protein AMN1 homolog; Antagonist of mitotic exit network 1 homolog | 0.544 |
EFHD1 | ERGIC2 | ENSP00000264059 | ENSP00000353270 | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | Endoplasmic reticulum-Golgi intermediate compartment protein 2; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family | 0.505 |
EFHD1 | ERMN | ENSP00000264059 | ENSP00000380453 | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | Ermin; Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity) | 0.698 |
EFHD1 | FAM19A2 | ENSP00000264059 | ENSP00000393987 | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | Protein FAM19A2; Family with sequence similarity 19 member A2, C-C motif chemokine like | 0.488 |
EFHD1 | KNDC1 | ENSP00000264059 | ENSP00000304437 | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence | 0.522 |
EFHD1 | NKAIN1 | ENSP00000264059 | ENSP00000362841 | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 | 0.494 |
EFHD1 | OPN5 | ENSP00000264059 | ENSP00000360255 | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | Opsin-5; Opsin receptors | 0.492 |
EFHD1 | RHAG | ENSP00000264059 | ENSP00000360217 | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | Ammonium transporter Rh type A; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Involved in ammonia transport across the erythrocyte membrane. Seems to act in monovalent cation transport; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily | 0.766 |
EFHD1 | STXBP5L | ENSP00000264059 | ENSP00000273666 | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | Syntaxin-binding protein 5-like; May play a role in vesicle trafficking and exocytosis; Belongs to the WD repeat L(2)GL family | 0.536 |
EFHD1 | TLK2 | ENSP00000264059 | ENSP00000316512 | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | Serine/threonine-protein kinase tousled-like 2; Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly. Negative regulator of amino acid starvation-induced autophagy | 0.485 |
ERGIC2 | EFHD1 | ENSP00000353270 | ENSP00000264059 | Endoplasmic reticulum-Golgi intermediate compartment protein 2; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | 0.505 |
ERMN | EFHD1 | ENSP00000380453 | ENSP00000264059 | Ermin; Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity) | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | 0.698 |
ERMN | KNDC1 | ENSP00000380453 | ENSP00000304437 | Ermin; Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity) | Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence | 0.615 |
FAM19A2 | EFHD1 | ENSP00000393987 | ENSP00000264059 | Protein FAM19A2; Family with sequence similarity 19 member A2, C-C motif chemokine like | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | 0.488 |
KNDC1 | EFHD1 | ENSP00000304437 | ENSP00000264059 | Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | 0.522 |
KNDC1 | ERMN | ENSP00000304437 | ENSP00000380453 | Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence | Ermin; Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity) | 0.615 |
NKAIN1 | EFHD1 | ENSP00000362841 | ENSP00000264059 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | 0.494 |
OPN5 | EFHD1 | ENSP00000360255 | ENSP00000264059 | Opsin-5; Opsin receptors | EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing | 0.492 |