| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CA3 | NOVA2 | ENSP00000285381 | ENSP00000263257 | Carbonic anhydrase 3; Reversible hydration of carbon dioxide; Carbonic anhydrases | RNA-binding protein Nova-2; May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA | 0.629 |
| FAM107B | NOVA1 | ENSP00000181796 | ENSP00000438875 | Protein FAM107B; Family with sequence similarity 107 member B | RNA-binding protein Nova-1; May regulate RNA splicing or metabolism in a specific subset of developing neurons | 0.711 |
| FAM107B | NOVA2 | ENSP00000181796 | ENSP00000263257 | Protein FAM107B; Family with sequence similarity 107 member B | RNA-binding protein Nova-2; May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA | 0.648 |
| FAM107B | PTBP1 | ENSP00000181796 | ENSP00000349428 | Protein FAM107B; Family with sequence similarity 107 member B | Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornav [...] | 0.426 |
| FAM107B | PTBP2 | ENSP00000181796 | ENSP00000359216 | Protein FAM107B; Family with sequence similarity 107 member B | Polypyrimidine tract-binding protein 2; RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA | 0.429 |
| FAM107B | RBFOX1 | ENSP00000181796 | ENSP00000309117 | Protein FAM107B; Family with sequence similarity 107 member B | RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | 0.424 |
| FAM107B | RBFOX2 | ENSP00000181796 | ENSP00000413035 | Protein FAM107B; Family with sequence similarity 107 member B | RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Prevents binding of U2AF2 to the 3’-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha | 0.535 |
| NOVA1 | FAM107B | ENSP00000438875 | ENSP00000181796 | RNA-binding protein Nova-1; May regulate RNA splicing or metabolism in a specific subset of developing neurons | Protein FAM107B; Family with sequence similarity 107 member B | 0.711 |
| NOVA1 | NOVA2 | ENSP00000438875 | ENSP00000263257 | RNA-binding protein Nova-1; May regulate RNA splicing or metabolism in a specific subset of developing neurons | RNA-binding protein Nova-2; May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA | 0.747 |
| NOVA1 | PTBP1 | ENSP00000438875 | ENSP00000349428 | RNA-binding protein Nova-1; May regulate RNA splicing or metabolism in a specific subset of developing neurons | Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornav [...] | 0.704 |
| NOVA1 | PTBP2 | ENSP00000438875 | ENSP00000359216 | RNA-binding protein Nova-1; May regulate RNA splicing or metabolism in a specific subset of developing neurons | Polypyrimidine tract-binding protein 2; RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA | 0.771 |
| NOVA1 | RBFOX1 | ENSP00000438875 | ENSP00000309117 | RNA-binding protein Nova-1; May regulate RNA splicing or metabolism in a specific subset of developing neurons | RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | 0.768 |
| NOVA1 | RBFOX2 | ENSP00000438875 | ENSP00000413035 | RNA-binding protein Nova-1; May regulate RNA splicing or metabolism in a specific subset of developing neurons | RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Prevents binding of U2AF2 to the 3’-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha | 0.749 |
| NOVA1 | SF1 | ENSP00000438875 | ENSP00000366604 | RNA-binding protein Nova-1; May regulate RNA splicing or metabolism in a specific subset of developing neurons | Splicing factor 1; Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5’-UACUAAC-3’ of the pre-mRNA. May act as transcription repressor; Spliceosomal A complex | 0.552 |
| NOVA1 | SRRM4 | ENSP00000438875 | ENSP00000267260 | RNA-binding protein Nova-1; May regulate RNA splicing or metabolism in a specific subset of developing neurons | Serine/arginine repetitive matrix protein 4; Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural- specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural- specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (By similarity) | 0.623 |
| NOVA2 | CA3 | ENSP00000263257 | ENSP00000285381 | RNA-binding protein Nova-2; May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA | Carbonic anhydrase 3; Reversible hydration of carbon dioxide; Carbonic anhydrases | 0.629 |
| NOVA2 | FAM107B | ENSP00000263257 | ENSP00000181796 | RNA-binding protein Nova-2; May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA | Protein FAM107B; Family with sequence similarity 107 member B | 0.648 |
| NOVA2 | NOVA1 | ENSP00000263257 | ENSP00000438875 | RNA-binding protein Nova-2; May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA | RNA-binding protein Nova-1; May regulate RNA splicing or metabolism in a specific subset of developing neurons | 0.747 |
| NOVA2 | PTBP1 | ENSP00000263257 | ENSP00000349428 | RNA-binding protein Nova-2; May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA | Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornav [...] | 0.652 |
| NOVA2 | PTBP2 | ENSP00000263257 | ENSP00000359216 | RNA-binding protein Nova-2; May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA | Polypyrimidine tract-binding protein 2; RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA | 0.712 |
