• Version:
  • 11.0 [archived version]
STRINGSTRING
ARHGAP25 ARHGAP25 SCRG1 SCRG1 GART GART FAM53B FAM53B CHCHD7 CHCHD7 LPPR5 LPPR5 TMEM25 TMEM25 SNX7 SNX7 SWSAP1 SWSAP1 PALMD PALMD GTDC1 GTDC1
"LPPR5" - Phospholipid phosphatase-related protein type 5 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
LPPR5Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family (321 aa)    
Predicted Functional Partners:
SWSAP1
ATPase SWSAP1; ATPase which is preferentially stimulated by single- stranded DNA and is involved in homologous recombination repair (HRR). Has a DNA-binding activity which is independent of its ATPase activity; CTLH complex (229 aa)
           
  0.668
SNX7
Sorting nexin-7; May be involved in several stages of intracellular trafficking; Belongs to the sorting nexin family (451 aa)
     
   
  0.665
FAM53B
Protein FAM53B; Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization (422 aa)
           
  0.599
PALMD
Palmdelphin (551 aa)
     
   
  0.562
CHCHD7
Mitochondrial coiled-coil-helix-coiled-coil-helix domain containing proteins; Belongs to the CHCHD7 family (110 aa)
           
  0.517
TMEM25
Transmembrane protein 25; C2-set domain containing (366 aa)
           
  0.514
SCRG1
Scrapie-responsive protein 1; Stimulator of chondrogenesis 1 (98 aa)
     
   
  0.493
GART
Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family (1010 aa)
         
  0.492
GTDC1
Glycosyltransferase-like domain-containing protein 1; Glycosyl transferases group 1 domain containing; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily (458 aa)
           
  0.477
ARHGAP25
Rho GTPase-activating protein 25; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state; Pleckstrin homology domain containing (646 aa)
           
  0.465
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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