node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARHGAP25 | LPPR5 | ENSP00000386911 | ENSP00000263177 | Rho GTPase-activating protein 25; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state; Pleckstrin homology domain containing | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | 0.465 |
CHCHD7 | FAM53B | ENSP00000306425 | ENSP00000338532 | Mitochondrial coiled-coil-helix-coiled-coil-helix domain containing proteins; Belongs to the CHCHD7 family | Protein FAM53B; Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization | 0.588 |
CHCHD7 | LPPR5 | ENSP00000306425 | ENSP00000263177 | Mitochondrial coiled-coil-helix-coiled-coil-helix domain containing proteins; Belongs to the CHCHD7 family | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | 0.517 |
FAM53B | CHCHD7 | ENSP00000338532 | ENSP00000306425 | Protein FAM53B; Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization | Mitochondrial coiled-coil-helix-coiled-coil-helix domain containing proteins; Belongs to the CHCHD7 family | 0.588 |
FAM53B | LPPR5 | ENSP00000338532 | ENSP00000263177 | Protein FAM53B; Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | 0.599 |
GART | LPPR5 | ENSP00000371253 | ENSP00000263177 | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | 0.492 |
GTDC1 | LPPR5 | ENSP00000376608 | ENSP00000263177 | Glycosyltransferase-like domain-containing protein 1; Glycosyl transferases group 1 domain containing; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | 0.477 |
GTDC1 | PALMD | ENSP00000376608 | ENSP00000263174 | Glycosyltransferase-like domain-containing protein 1; Glycosyl transferases group 1 domain containing; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | Palmdelphin | 0.440 |
GTDC1 | SNX7 | ENSP00000376608 | ENSP00000304429 | Glycosyltransferase-like domain-containing protein 1; Glycosyl transferases group 1 domain containing; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | Sorting nexin-7; May be involved in several stages of intracellular trafficking; Belongs to the sorting nexin family | 0.414 |
LPPR5 | ARHGAP25 | ENSP00000263177 | ENSP00000386911 | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | Rho GTPase-activating protein 25; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state; Pleckstrin homology domain containing | 0.465 |
LPPR5 | CHCHD7 | ENSP00000263177 | ENSP00000306425 | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | Mitochondrial coiled-coil-helix-coiled-coil-helix domain containing proteins; Belongs to the CHCHD7 family | 0.517 |
LPPR5 | FAM53B | ENSP00000263177 | ENSP00000338532 | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | Protein FAM53B; Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization | 0.599 |
LPPR5 | GART | ENSP00000263177 | ENSP00000371253 | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family | 0.492 |
LPPR5 | GTDC1 | ENSP00000263177 | ENSP00000376608 | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | Glycosyltransferase-like domain-containing protein 1; Glycosyl transferases group 1 domain containing; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | 0.477 |
LPPR5 | PALMD | ENSP00000263177 | ENSP00000263174 | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | Palmdelphin | 0.562 |
LPPR5 | SCRG1 | ENSP00000263177 | ENSP00000296506 | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | Scrapie-responsive protein 1; Stimulator of chondrogenesis 1 | 0.493 |
LPPR5 | SNX7 | ENSP00000263177 | ENSP00000304429 | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | Sorting nexin-7; May be involved in several stages of intracellular trafficking; Belongs to the sorting nexin family | 0.665 |
LPPR5 | SWSAP1 | ENSP00000263177 | ENSP00000310008 | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | ATPase SWSAP1; ATPase which is preferentially stimulated by single- stranded DNA and is involved in homologous recombination repair (HRR). Has a DNA-binding activity which is independent of its ATPase activity; CTLH complex | 0.668 |
LPPR5 | TMEM25 | ENSP00000263177 | ENSP00000315635 | Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family | Transmembrane protein 25; C2-set domain containing | 0.514 |
PALMD | GTDC1 | ENSP00000263174 | ENSP00000376608 | Palmdelphin | Glycosyltransferase-like domain-containing protein 1; Glycosyl transferases group 1 domain containing; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | 0.440 |