SLC17A6 protein (human) - STRING database

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SLC17A6

Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily (582 aa)

Predicted Functional Partners:

SLC32A1

0.987

SLC18A3

0.958

SLC18A2

0.919

SLC18A1

0.882

GAD2

0.860

GAD1

0.843

SLC17A7

0.838

SLC17A8

0.811

SYP

0.774

SYN1

0.750

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAD1	GAD2	ENSP00000350928	ENSP00000365437	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Glutamate decarboxylase 2; Catalyzes the production of GABA	0.956
GAD1	SLC17A6	ENSP00000350928	ENSP00000263160	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily	0.843
GAD1	SLC17A7	ENSP00000350928	ENSP00000221485	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Vesicular glutamate transporter 1; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate; Solute carriers	0.849
GAD1	SLC17A8	ENSP00000350928	ENSP00000316909	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Vesicular glutamate transporter 3; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate; Deafness associated genes	0.651
GAD1	SLC18A2	ENSP00000350928	ENSP00000298472	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Synaptic vesicular amine transporter; Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis; Belongs to the major facilitator superfamily. Vesicular transporter family	0.513
GAD1	SLC18A3	ENSP00000350928	ENSP00000363229	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Vesicular acetylcholine transporter; Involved in acetylcholine transport into synaptic vesicles; Solute carriers	0.727
GAD1	SLC32A1	ENSP00000350928	ENSP00000217420	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Solute carriers	0.999
GAD1	SYN1	ENSP00000350928	ENSP00000295987	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Synapsin-1; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level; Synapsins	0.591
GAD1	SYP	ENSP00000350928	ENSP00000263233	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Synaptophysin; Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity); Synaptophysins	0.657
GAD2	GAD1	ENSP00000365437	ENSP00000350928	Glutamate decarboxylase 2; Catalyzes the production of GABA	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	0.956
GAD2	SLC17A6	ENSP00000365437	ENSP00000263160	Glutamate decarboxylase 2; Catalyzes the production of GABA	Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily	0.860
GAD2	SLC17A7	ENSP00000365437	ENSP00000221485	Glutamate decarboxylase 2; Catalyzes the production of GABA	Vesicular glutamate transporter 1; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate; Solute carriers	0.856
GAD2	SLC17A8	ENSP00000365437	ENSP00000316909	Glutamate decarboxylase 2; Catalyzes the production of GABA	Vesicular glutamate transporter 3; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate; Deafness associated genes	0.593
GAD2	SLC18A2	ENSP00000365437	ENSP00000298472	Glutamate decarboxylase 2; Catalyzes the production of GABA	Synaptic vesicular amine transporter; Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis; Belongs to the major facilitator superfamily. Vesicular transporter family	0.448
GAD2	SLC18A3	ENSP00000365437	ENSP00000363229	Glutamate decarboxylase 2; Catalyzes the production of GABA	Vesicular acetylcholine transporter; Involved in acetylcholine transport into synaptic vesicles; Solute carriers	0.659
GAD2	SLC32A1	ENSP00000365437	ENSP00000217420	Glutamate decarboxylase 2; Catalyzes the production of GABA	Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Solute carriers	0.994
GAD2	SYN1	ENSP00000365437	ENSP00000295987	Glutamate decarboxylase 2; Catalyzes the production of GABA	Synapsin-1; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level; Synapsins	0.699
GAD2	SYP	ENSP00000365437	ENSP00000263233	Glutamate decarboxylase 2; Catalyzes the production of GABA	Synaptophysin; Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity); Synaptophysins	0.714
SLC17A6	GAD1	ENSP00000263160	ENSP00000350928	Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	0.843
SLC17A6	GAD2	ENSP00000263160	ENSP00000365437	Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily	Glutamate decarboxylase 2; Catalyzes the production of GABA	0.860

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