• Version:
  • 11.0 [archived version]
STRINGSTRING
PRR14 PRR14 MRPL54 MRPL54 SBK2 SBK2 ATCAY ATCAY TSPYL6 TSPYL6 NMRK2 NMRK2 ZFR2 ZFR2 PLEKHD1 PLEKHD1 SPATC1 SPATC1 ZNF169 ZNF169 ILF2 ILF2
"ZFR2" - Zinc finger RNA binding protein 2 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZFR2Zinc finger RNA binding protein 2 (939 aa)    
Predicted Functional Partners:
ILF2
Interleukin enhancer-binding factor 2; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus (390 aa)
       
   
0.816
PLEKHD1
Pleckstrin homology and coiled-coil domain containing D1; Belongs to the PLEKHD1 family (506 aa)
           
  0.571
TSPYL6
Testis-specific Y-encoded-like protein 6; TSPY like 6 (410 aa)
     
   
  0.560
ATCAY
Caytaxin; Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter. Alternatively, may regulate the localization of mitochondria within axons and dendrites; BCH domain containing (371 aa)
     
   
  0.522
SPATC1
Speriolin; Spermatogenesis and centriole associated 1; Belongs to the speriolin family (591 aa)
           
  0.517
ZNF169
Zinc finger protein 169; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (603 aa)
           
  0.516
PRR14
Proline-rich protein 14; Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha. Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit. Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha. Involved in the positive regulation of the PI3K-Akt-mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2 (585 aa)
     
   
  0.490
MRPL54
Mitochondrial ribosomal protein L54 (138 aa)
     
   
  0.483
SBK2
Serine/threonine-protein kinase SBK2; SH3 domain binding kinase family member 2 (348 aa)
           
  0.475
NMRK2
Nicotinamide riboside kinase 2; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis; Belongs to the uridine kinase family. NRK subfamily (235 aa)
     
   
  0.456
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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