node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATCAY | NMRK2 | ENSP00000390941 | ENSP00000480091 | Caytaxin; Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter. Alternatively, may regulate the localization of mitochondria within axons and dendrites; BCH domain containing | Nicotinamide riboside kinase 2; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis; Belongs to the uridine kinase family. NRK subfamily | 0.471 |
ATCAY | ZFR2 | ENSP00000390941 | ENSP00000262961 | Caytaxin; Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter. Alternatively, may regulate the localization of mitochondria within axons and dendrites; BCH domain containing | Zinc finger RNA binding protein 2 | 0.522 |
ILF2 | ZFR2 | ENSP00000355011 | ENSP00000262961 | Interleukin enhancer-binding factor 2; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus | Zinc finger RNA binding protein 2 | 0.816 |
MRPL54 | ZFR2 | ENSP00000331849 | ENSP00000262961 | Mitochondrial ribosomal protein L54 | Zinc finger RNA binding protein 2 | 0.483 |
NMRK2 | ATCAY | ENSP00000480091 | ENSP00000390941 | Nicotinamide riboside kinase 2; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis; Belongs to the uridine kinase family. NRK subfamily | Caytaxin; Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter. Alternatively, may regulate the localization of mitochondria within axons and dendrites; BCH domain containing | 0.471 |
NMRK2 | ZFR2 | ENSP00000480091 | ENSP00000262961 | Nicotinamide riboside kinase 2; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis; Belongs to the uridine kinase family. NRK subfamily | Zinc finger RNA binding protein 2 | 0.456 |
PLEKHD1 | ZFR2 | ENSP00000317175 | ENSP00000262961 | Pleckstrin homology and coiled-coil domain containing D1; Belongs to the PLEKHD1 family | Zinc finger RNA binding protein 2 | 0.571 |
PRR14 | SBK2 | ENSP00000441641 | ENSP00000389015 | Proline-rich protein 14; Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha. Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit. Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha. Involved in the positive regulation of the PI3K-Akt-mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2 | Serine/threonine-protein kinase SBK2; SH3 domain binding kinase family member 2 | 0.593 |
PRR14 | ZFR2 | ENSP00000441641 | ENSP00000262961 | Proline-rich protein 14; Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha. Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit. Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha. Involved in the positive regulation of the PI3K-Akt-mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2 | Zinc finger RNA binding protein 2 | 0.490 |
SBK2 | PRR14 | ENSP00000389015 | ENSP00000441641 | Serine/threonine-protein kinase SBK2; SH3 domain binding kinase family member 2 | Proline-rich protein 14; Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha. Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit. Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha. Involved in the positive regulation of the PI3K-Akt-mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2 | 0.593 |
SBK2 | ZFR2 | ENSP00000389015 | ENSP00000262961 | Serine/threonine-protein kinase SBK2; SH3 domain binding kinase family member 2 | Zinc finger RNA binding protein 2 | 0.475 |
SPATC1 | ZFR2 | ENSP00000366690 | ENSP00000262961 | Speriolin; Spermatogenesis and centriole associated 1; Belongs to the speriolin family | Zinc finger RNA binding protein 2 | 0.517 |
TSPYL6 | ZFR2 | ENSP00000417919 | ENSP00000262961 | Testis-specific Y-encoded-like protein 6; TSPY like 6 | Zinc finger RNA binding protein 2 | 0.560 |
ZFR2 | ATCAY | ENSP00000262961 | ENSP00000390941 | Zinc finger RNA binding protein 2 | Caytaxin; Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter. Alternatively, may regulate the localization of mitochondria within axons and dendrites; BCH domain containing | 0.522 |
ZFR2 | ILF2 | ENSP00000262961 | ENSP00000355011 | Zinc finger RNA binding protein 2 | Interleukin enhancer-binding factor 2; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus | 0.816 |
ZFR2 | MRPL54 | ENSP00000262961 | ENSP00000331849 | Zinc finger RNA binding protein 2 | Mitochondrial ribosomal protein L54 | 0.483 |
ZFR2 | NMRK2 | ENSP00000262961 | ENSP00000480091 | Zinc finger RNA binding protein 2 | Nicotinamide riboside kinase 2; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis; Belongs to the uridine kinase family. NRK subfamily | 0.456 |
ZFR2 | PLEKHD1 | ENSP00000262961 | ENSP00000317175 | Zinc finger RNA binding protein 2 | Pleckstrin homology and coiled-coil domain containing D1; Belongs to the PLEKHD1 family | 0.571 |
ZFR2 | PRR14 | ENSP00000262961 | ENSP00000441641 | Zinc finger RNA binding protein 2 | Proline-rich protein 14; Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha. Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit. Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha. Involved in the positive regulation of the PI3K-Akt-mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2 | 0.490 |
ZFR2 | SBK2 | ENSP00000262961 | ENSP00000389015 | Zinc finger RNA binding protein 2 | Serine/threonine-protein kinase SBK2; SH3 domain binding kinase family member 2 | 0.475 |