• Version:
  • 11.0 [archived version]
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KTN1 KTN1 CTDSP2 CTDSP2 PCDH19 PCDH19 NINL NINL RAPH1 RAPH1 QRICH2 QRICH2 QRICH1 QRICH1 C10orf107 C10orf107 KANSL3 KANSL3 C8orf86 C8orf86 KRTAP11-1 KRTAP11-1
"QRICH2" - Glutamine-rich protein 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
QRICH2Glutamine-rich protein 2; Glutamine rich 2 (1663 aa)    
Predicted Functional Partners:
QRICH1
Glutamine-rich protein 1; Glutamine rich 1 (776 aa)
           
  0.780
C10orf107
Ciliary-associated calcium-binding coiled-coil protein 1; Calcium-binding protein. May be involved in the control of sperm flagellar movement (208 aa)
           
  0.590
C8orf86
Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86 (223 aa)
           
  0.584
RAPH1
Ras-associated and pleckstrin homology domains-containing protein 1; Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion; Pleckstrin homology domain containing (1250 aa)
           
  0.562
NINL
Ninein-like protein; Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly. May play a role in ovarian carcinogenesis; EF-hand domain containing (1382 aa)
           
  0.547
PCDH19
Protocadherin-19; Potential calcium-dependent cell-adhesion protein; Non-clustered protocadherins (1148 aa)
           
  0.546
KTN1
Kinectin; Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin; Belongs to the kinectin family (1357 aa)
           
  0.544
KANSL3
KAT8 regulatory NSL complex subunit 3; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription (878 aa)
           
  0.532
KRTAP11-1
Keratin-associated protein 11-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins (163 aa)
           
  0.527
CTDSP2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; Preferentially catalyzes the dephosphorylation of ’Ser- 5’ within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas; CTD family phosphatases (271 aa)
           
  0.504
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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