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  • 11.0 [archived version]
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HORMAD1 HORMAD1 SYNRG SYNRG C15orf52 C15orf52 LYSMD4 LYSMD4 YLPM1 YLPM1 LOC81691 LOC81691 C17orf77 C17orf77 REXO2 REXO2 REXO1 REXO1 TBL3 TBL3 TRMT6 TRMT6
"LOC81691" - Putative RNA exonuclease NEF-sp in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC81691Putative RNA exonuclease NEF-sp (774 aa)    
Predicted Functional Partners:
REXO2
Oligoribonuclease, mitochondrial; 3’-to-5’ exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role in cellular nucleotide recycling; Exonucleases (237 aa)
     
  0.904
REXO1
RNA exonuclease 1 homolog; Seems to have no detectable effect on transcription elongation in vitro; Belongs to the REXO1/REXO3 family (1221 aa)
     
 
0.845
C17orf77
Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 (243 aa)
           
  0.589
LYSMD4
LysM and putative peptidoglycan-binding domain-containing protein 4; LysM domain containing 4 (297 aa)
           
  0.586
SYNRG
Synergin gamma; May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins (1314 aa)
     
 
  0.567
C15orf52
Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 (534 aa)
           
  0.558
TBL3
Transducin beta-like protein 3; WD repeat domain containing; UTPb subcomplex (808 aa)
     
   
  0.525
HORMAD1
HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis- ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint- required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process be [...] (394 aa)
     
   
  0.514
YLPM1
YLP motif-containing protein 1; Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation; Protein phosphatase 1 regulatory subunits (2146 aa)
           
  0.506
TRMT6
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs- N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries (497 aa)
     
 
  0.492
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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