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  • 11.0 [archived version]
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SCHIP1 SCHIP1 RBM19 RBM19 NXPE3 NXPE3 RGL4 RGL4 TM9SF3 TM9SF3 C12orf49 C12orf49 KIFC3 KIFC3 SOWAHC SOWAHC USP54 USP54 LANCL1 LANCL1 SYNGR3 SYNGR3
"C12orf49" - UPF0454 protein C12orf49 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
C12orf49UPF0454 protein C12orf49; Chromosome 12 open reading frame 49; Belongs to the UPF0454 family (205 aa)    
Predicted Functional Partners:
NXPE3
NXPE family member 3; Neurexophilin and PC-esterase domain family member 3 (559 aa)
           
  0.815
RGL4
Ral-GDS-related protein; Ral guanine nucleotide dissociation stimulator like 4 (473 aa)
           
  0.630
SOWAHC
Ankyrin repeat domain-containing protein SOWAHC; Sosondowah ankyrin repeat domain family member C; Belongs to the SOWAH family (525 aa)
           
  0.588
RBM19
Probable RNA-binding protein 19; Plays a role in embryo pre-implantation development; RNA binding motif containing (960 aa)
           
  0.581
TM9SF3
Transmembrane 9 superfamily member 3 (589 aa)
     
   
  0.540
USP54
Inactive ubiquitin carboxyl-terminal hydrolase 54; Has no peptidase activity; Belongs to the peptidase C19 family (1684 aa)
           
  0.533
SYNGR3
Synaptogyrin-3; May play a role in regulated exocytosis. May indirectly regulate the activity of the plasma membrane dopamine transporter SLC6A3 and thereby regulate dopamine transport back from the synaptic cleft into the presynaptic terminal; Belongs to the synaptogyrin family (229 aa)
           
  0.491
LANCL1
LanC-like protein 1; May play a role in EPS8 signaling. Binds glutathione (399 aa)
           
  0.489
KIFC3
Kinesin-like protein KIFC3; Minus-end microtubule-dependent motor protein. Involved in apically targeted transport (By similarity). Required for zonula adherens maintenance; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family (833 aa)
           
  0.475
SCHIP1
Schwannomin interacting protein 1, isoform CRA_c; May play a role in action potential conduction in myelinated cells through the organization of molecular complexes at nodes of Ranvier and axon initial segments. May also play a role in axon outgrowth and guidance (By similarity) (244 aa)
           
  0.471
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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