node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC167 | TMCC3 | ENSP00000362507 | ENSP00000261226 | Coiled-coil domain containing 167 | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | 0.553 |
CLCA4 | EDIL3 | ENSP00000359594 | ENSP00000296591 | Calcium-activated chloride channel regulator 4; May be involved in mediating calcium-activated chloride conductance; Chloride channel accessory | EGF-like repeat and discoidin I-like domain-containing protein 3; Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development | 0.564 |
CLCA4 | TMCC3 | ENSP00000359594 | ENSP00000261226 | Calcium-activated chloride channel regulator 4; May be involved in mediating calcium-activated chloride conductance; Chloride channel accessory | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | 0.625 |
CLCA4 | TMTC4 | ENSP00000359594 | ENSP00000343871 | Calcium-activated chloride channel regulator 4; May be involved in mediating calcium-activated chloride conductance; Chloride channel accessory | Transmembrane and tetratricopeptide repeat containing 4; Belongs to the TMTC family | 0.606 |
EDIL3 | CLCA4 | ENSP00000296591 | ENSP00000359594 | EGF-like repeat and discoidin I-like domain-containing protein 3; Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development | Calcium-activated chloride channel regulator 4; May be involved in mediating calcium-activated chloride conductance; Chloride channel accessory | 0.564 |
EDIL3 | TMCC3 | ENSP00000296591 | ENSP00000261226 | EGF-like repeat and discoidin I-like domain-containing protein 3; Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | 0.623 |
EDIL3 | TMTC4 | ENSP00000296591 | ENSP00000343871 | EGF-like repeat and discoidin I-like domain-containing protein 3; Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development | Transmembrane and tetratricopeptide repeat containing 4; Belongs to the TMTC family | 0.614 |
EDIL3 | UNC79 | ENSP00000296591 | ENSP00000256339 | EGF-like repeat and discoidin I-like domain-containing protein 3; Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development | Protein unc-79 homolog; Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability; Belongs to the unc-79 family | 0.519 |
FBXO28 | TMCC3 | ENSP00000355827 | ENSP00000261226 | F-box only protein 28; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | 0.647 |
PRICKLE1 | TMCC3 | ENSP00000345064 | ENSP00000261226 | Prickle-like protein 1; Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor; LIM domain containing | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | 0.610 |
TEX28 | TMCC3 | ENSP00000478834 | ENSP00000261226 | Testis-specific protein TEX28; Testis expressed 28; Belongs to the TEX28 family | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | 0.733 |
TMCC3 | CCDC167 | ENSP00000261226 | ENSP00000362507 | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | Coiled-coil domain containing 167 | 0.553 |
TMCC3 | CLCA4 | ENSP00000261226 | ENSP00000359594 | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | Calcium-activated chloride channel regulator 4; May be involved in mediating calcium-activated chloride conductance; Chloride channel accessory | 0.625 |
TMCC3 | EDIL3 | ENSP00000261226 | ENSP00000296591 | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | EGF-like repeat and discoidin I-like domain-containing protein 3; Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development | 0.623 |
TMCC3 | FBXO28 | ENSP00000261226 | ENSP00000355827 | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | F-box only protein 28; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other | 0.647 |
TMCC3 | PRICKLE1 | ENSP00000261226 | ENSP00000345064 | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | Prickle-like protein 1; Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor; LIM domain containing | 0.610 |
TMCC3 | TEX28 | ENSP00000261226 | ENSP00000478834 | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | Testis-specific protein TEX28; Testis expressed 28; Belongs to the TEX28 family | 0.733 |
TMCC3 | TMEM125 | ENSP00000261226 | ENSP00000429275 | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | Transmembrane protein 125 | 0.718 |
TMCC3 | TMTC4 | ENSP00000261226 | ENSP00000343871 | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | Transmembrane and tetratricopeptide repeat containing 4; Belongs to the TMTC family | 0.765 |
TMCC3 | UGT8 | ENSP00000261226 | ENSP00000311648 | Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system; Belongs to the UDP-glycosyltransferase family | 0.557 |