• Version:
  • 11.0 [archived version]
STRINGSTRING
TEX28 TEX28 TMEM125 TMEM125 CCDC167 CCDC167 TMCC3 TMCC3 FBXO28 FBXO28 CLCA4 CLCA4 EDIL3 EDIL3 TMTC4 TMTC4 UNC79 UNC79 PRICKLE1 PRICKLE1 UGT8 UGT8
"TMCC3" - Transmembrane and coiled-coil domain containing in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
Coexpression
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[Homology]
Score
TMCC3Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family (477 aa)    
Predicted Functional Partners:
TMTC4
Transmembrane and tetratricopeptide repeat containing 4; Belongs to the TMTC family (760 aa)
           
  0.765
TEX28
Testis-specific protein TEX28; Testis expressed 28; Belongs to the TEX28 family (410 aa)
       
 
0.733
TMEM125
Transmembrane protein 125 (219 aa)
           
  0.718
FBXO28
F-box only protein 28; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other (368 aa)
       
      0.647
CLCA4
Calcium-activated chloride channel regulator 4; May be involved in mediating calcium-activated chloride conductance; Chloride channel accessory (919 aa)
     
   
  0.625
EDIL3
EGF-like repeat and discoidin I-like domain-containing protein 3; Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development (480 aa)
           
  0.623
PRICKLE1
Prickle-like protein 1; Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor; LIM domain containing (831 aa)
       
 
  0.610
UNC79
Protein unc-79 homolog; Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability; Belongs to the unc-79 family (2458 aa)
           
  0.566
UGT8
2-hydroxyacylsphingosine 1-beta-galactosyltransferase; Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system; Belongs to the UDP-glycosyltransferase family (541 aa)
           
  0.557
CCDC167
Coiled-coil domain containing 167 (97 aa)
           
  0.553
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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