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  • 11.0 [archived version]
STRINGSTRING
CRACR2A CRACR2A CMTM6 CMTM6 NRIP2 NRIP2 TSGA10IP TSGA10IP TSPAN11 TSPAN11 GHITM GHITM TRMT13 TRMT13 RNF214 RNF214 PCLO PCLO TSPAN13 TSPAN13 TSPAN32 TSPAN32
"TSPAN11" - Tetraspanin-11 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSPAN11Tetraspanin-11; Tetraspanin 11; Tetraspanins (253 aa)    
Predicted Functional Partners:
GHITM
Growth hormone-inducible transmembrane protein; Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c; Transmembrane BAX inhibitor motif containing (345 aa)
            
  0.704
TSGA10IP
Testis specific 10 interacting protein (556 aa)
            
  0.582
NRIP2
Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 (281 aa)
            
  0.569
CMTM6
CKLF like MARVEL transmembrane domain containing 6; Belongs to the chemokine-like factor family (183 aa)
      
   
  0.540
TRMT13
tRNA-m(4)X modification enzyme TRM13 homolog; tRNA methylase which 2’-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His) (481 aa)
            
  0.540
TSPAN13
Tetraspanin-13; Tetraspanin 13; Tetraspanins (204 aa)
            
  0.516
RNF214
Ring finger protein 214 (703 aa)
            
  0.510
CRACR2A
EF-hand calcium-binding domain-containing protein 4B; Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from OR [...] (731 aa)
            
  0.500
TSPAN32
Tetraspanin-32; Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family (320 aa)
            
  0.474
PCLO
Protein piccolo; May act as a scaffolding protein involved in the organization of synaptic active zones and in synaptic vesicle trafficking; C2 domain containing (5142 aa)
      
   
  0.474
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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