| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASNSD1 | CCT3 | ENSP00000260952 | ENSP00000295688 | Asparagine synthetase domain containing 1 | T-complex protein 1 subunit gamma; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin; Chaperonins | 0.649 |
| ASNSD1 | FAM193B | ENSP00000260952 | ENSP00000422131 | Asparagine synthetase domain containing 1 | Protein FAM193B; Family with sequence similarity 193 member B; Belongs to the FAM193 family | 0.659 |
| ASNSD1 | HIBCH | ENSP00000260952 | ENSP00000352706 | Asparagine synthetase domain containing 1 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA | 0.691 |
| ASNSD1 | MS4A14 | ENSP00000260952 | ENSP00000433761 | Asparagine synthetase domain containing 1 | Membrane-spanning 4-domains subfamily A member 14; May be involved in signal transduction as a component of a multimeric receptor complex; Membrane spanning 4-domains | 0.634 |
| ASNSD1 | ORMDL1 | ENSP00000260952 | ENSP00000326869 | Asparagine synthetase domain containing 1 | ORM1-like protein 1; Negative regulator of sphingolipid synthesis | 0.676 |
| ASNSD1 | PMS1 | ENSP00000260952 | ENSP00000406490 | Asparagine synthetase domain containing 1 | PMS1 protein homolog 1; Probably involved in the repair of mismatches in DNA | 0.628 |
| ASNSD1 | PPP1R35 | ENSP00000260952 | ENSP00000292330 | Asparagine synthetase domain containing 1 | Protein phosphatase 1 regulatory subunit 35; Inhibits PPP1CA phosphatase activity; Protein phosphatase 1 regulatory subunits | 0.743 |
| ASNSD1 | PRR7 | ENSP00000260952 | ENSP00000327168 | Asparagine synthetase domain containing 1 | Proline-rich protein 7; Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN. Might play a redundant role in the regulation of T cell receptor signaling. Might promote apoptosis in T cells | 0.642 |
| ASNSD1 | TMED9 | ENSP00000260952 | ENSP00000330945 | Asparagine synthetase domain containing 1 | Transmembrane emp24 domain-containing protein 9; Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer- dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of [...] | 0.655 |
| ASNSD1 | TMEM194B | ENSP00000260952 | ENSP00000386292 | Asparagine synthetase domain containing 1 | Nuclear envelope integral membrane protein 2; Transmembrane protein 194B; Belongs to the NEMP family | 0.668 |
| CCT3 | ASNSD1 | ENSP00000295688 | ENSP00000260952 | T-complex protein 1 subunit gamma; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin; Chaperonins | Asparagine synthetase domain containing 1 | 0.649 |
| FAM193B | ASNSD1 | ENSP00000422131 | ENSP00000260952 | Protein FAM193B; Family with sequence similarity 193 member B; Belongs to the FAM193 family | Asparagine synthetase domain containing 1 | 0.659 |
| FAM193B | HIBCH | ENSP00000422131 | ENSP00000352706 | Protein FAM193B; Family with sequence similarity 193 member B; Belongs to the FAM193 family | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA | 0.714 |
| FAM193B | ORMDL1 | ENSP00000422131 | ENSP00000326869 | Protein FAM193B; Family with sequence similarity 193 member B; Belongs to the FAM193 family | ORM1-like protein 1; Negative regulator of sphingolipid synthesis | 0.590 |
| FAM193B | PMS1 | ENSP00000422131 | ENSP00000406490 | Protein FAM193B; Family with sequence similarity 193 member B; Belongs to the FAM193 family | PMS1 protein homolog 1; Probably involved in the repair of mismatches in DNA | 0.649 |
| FAM193B | PRR7 | ENSP00000422131 | ENSP00000327168 | Protein FAM193B; Family with sequence similarity 193 member B; Belongs to the FAM193 family | Proline-rich protein 7; Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN. Might play a redundant role in the regulation of T cell receptor signaling. Might promote apoptosis in T cells | 0.698 |
| FAM193B | TMED9 | ENSP00000422131 | ENSP00000330945 | Protein FAM193B; Family with sequence similarity 193 member B; Belongs to the FAM193 family | Transmembrane emp24 domain-containing protein 9; Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer- dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of [...] | 0.725 |
| HIBCH | ASNSD1 | ENSP00000352706 | ENSP00000260952 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA | Asparagine synthetase domain containing 1 | 0.691 |
| HIBCH | FAM193B | ENSP00000352706 | ENSP00000422131 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA | Protein FAM193B; Family with sequence similarity 193 member B; Belongs to the FAM193 family | 0.714 |
| HIBCH | ORMDL1 | ENSP00000352706 | ENSP00000326869 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA | ORM1-like protein 1; Negative regulator of sphingolipid synthesis | 0.713 |
