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STRINGSTRING
ALDOB ALDOB SI SI ALDOA ALDOA HK3 HK3 ALDOC ALDOC HK1 HK1 HKDC1 HKDC1 KHK KHK HK2 HK2 SORD SORD FUK FUK
"KHK" - Ketohexokinase in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
KHKKetohexokinase; Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate; Belongs to the carbohydrate kinase PfkB family (298 aa)    
Predicted Functional Partners:
HK1
Hexokinase-1; Hexokinase 1 (921 aa)
      
 
  0.971
ALDOB
Aldolase, fructose-bisphosphate B (364 aa)
      
 
  0.957
SORD
Sorbitol dehydrogenase; Converts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm; Belongs to the zinc-containing alcohol dehydrogenase family (357 aa)
      
 
  0.956
ALDOC
Aldolase, fructose-bisphosphate C (364 aa)
      
 
  0.930
HK2
Hexokinase-2; Hexokinase 2; Belongs to the hexokinase family (917 aa)
      
 
  0.928
ALDOA
Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family (418 aa)
      
 
  0.927
SI
Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family (1827 aa)
      
 
  0.910
HK3
Hexokinase-3; Hexokinase 3 (923 aa)
      
 
  0.905
HKDC1
Putative hexokinase HKDC1; Hexokinase domain containing 1 (917 aa)
      
 
    0.902
FUK
L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides (1084 aa)
          
    0.800
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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