CTDSPL2 protein (human) - STRING database

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CTDSPL2

CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases (466 aa)

Predicted Functional Partners:

ZCCHC10

0.707

TMEM135

0.674

TMEM87A

0.651

TBC1D32

0.634

FAM49B

0.607

CXorf57

0.599

UBLCP1

0.594

USP38

0.570

QRSL1

0.563

WDFY1

0.558

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTDSPL2	CXorf57	ENSP00000260327	ENSP00000361628	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	RPA-related protein RADX; Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability. Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks	0.599
CTDSPL2	FAM49B	ENSP00000260327	ENSP00000429150	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	Protein FAM49B; Family with sequence similarity 49 member B	0.607
CTDSPL2	QRSL1	ENSP00000260327	ENSP00000358042	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln)	0.563
CTDSPL2	TBC1D32	ENSP00000260327	ENSP00000381270	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	Protein broad-minded; Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling (By similarity); Armadillo-like helical domain containing	0.634
CTDSPL2	TMEM135	ENSP00000260327	ENSP00000306344	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	Transmembrane protein 135; Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission. May act as a regulator of mitochondrial fission that promotes DNM1L-dependent fission through activation of DNM1L. May be involved in peroxisome organization; Belongs to the TMEM135 family	0.674
CTDSPL2	TMEM87A	ENSP00000260327	ENSP00000374484	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN)	0.651
CTDSPL2	UBLCP1	ENSP00000260327	ENSP00000296786	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	Ubiquitin-like domain-containing CTD phosphatase 1; Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome; CTD family phosphatases	0.594
CTDSPL2	USP38	ENSP00000260327	ENSP00000303434	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	Ubiquitin carboxyl-terminal hydrolase 38; Deubiquitinating enzyme exhibiting a preference towards ’Lys-63’-linked ubiquitin chains; Belongs to the peptidase C19 family	0.570
CTDSPL2	WDFY1	ENSP00000260327	ENSP00000233055	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	WD repeat and FYVE domain-containing protein 1; Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines; WD repeat domain containing	0.558
CTDSPL2	ZCCHC10	ENSP00000260327	ENSP00000423276	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	Zinc finger CCHC-type containing 10	0.707
CXorf57	CTDSPL2	ENSP00000361628	ENSP00000260327	RPA-related protein RADX; Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability. Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	0.599
CXorf57	FAM49B	ENSP00000361628	ENSP00000429150	RPA-related protein RADX; Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability. Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks	Protein FAM49B; Family with sequence similarity 49 member B	0.537
CXorf57	TMEM135	ENSP00000361628	ENSP00000306344	RPA-related protein RADX; Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability. Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks	Transmembrane protein 135; Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission. May act as a regulator of mitochondrial fission that promotes DNM1L-dependent fission through activation of DNM1L. May be involved in peroxisome organization; Belongs to the TMEM135 family	0.605
CXorf57	ZCCHC10	ENSP00000361628	ENSP00000423276	RPA-related protein RADX; Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability. Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks	Zinc finger CCHC-type containing 10	0.625
FAM49B	CTDSPL2	ENSP00000429150	ENSP00000260327	Protein FAM49B; Family with sequence similarity 49 member B	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	0.607
FAM49B	CXorf57	ENSP00000429150	ENSP00000361628	Protein FAM49B; Family with sequence similarity 49 member B	RPA-related protein RADX; Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability. Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks	0.537
FAM49B	TMEM135	ENSP00000429150	ENSP00000306344	Protein FAM49B; Family with sequence similarity 49 member B	Transmembrane protein 135; Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission. May act as a regulator of mitochondrial fission that promotes DNM1L-dependent fission through activation of DNM1L. May be involved in peroxisome organization; Belongs to the TMEM135 family	0.611
FAM49B	ZCCHC10	ENSP00000429150	ENSP00000423276	Protein FAM49B; Family with sequence similarity 49 member B	Zinc finger CCHC-type containing 10	0.676
QRSL1	CTDSPL2	ENSP00000358042	ENSP00000260327	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln)	CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases	0.563
QRSL1	USP38	ENSP00000358042	ENSP00000303434	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln)	Ubiquitin carboxyl-terminal hydrolase 38; Deubiquitinating enzyme exhibiting a preference towards ’Lys-63’-linked ubiquitin chains; Belongs to the peptidase C19 family	0.508

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