| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASMTL | METTL10 | ENSP00000370718 | ENSP00000357829 | N-acetylserotonin O-methyltransferase-like protein; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity; In the N-terminal section; belongs to the maf family | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | 0.673 |
| ASMTL | METTL9 | ENSP00000370718 | ENSP00000350874 | N-acetylserotonin O-methyltransferase-like protein; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity; In the N-terminal section; belongs to the maf family | Methyltransferase-like protein 9; Methyltransferase like 9 | 0.605 |
| ASMTL | MTRF1L | ENSP00000370718 | ENSP00000356202 | N-acetylserotonin O-methyltransferase-like protein; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity; In the N-terminal section; belongs to the maf family | Peptide chain release factor 1-like, mitochondrial; Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG | 0.551 |
| ASMTL | RRNAD1 | ENSP00000370718 | ENSP00000357199 | N-acetylserotonin O-methyltransferase-like protein; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity; In the N-terminal section; belongs to the maf family | Protein RRNAD1; Ribosomal RNA adenine dimethylase domain containing 1; Belongs to the RRNAD1 family | 0.640 |
| ASMTL | RSAD1 | ENSP00000370718 | ENSP00000258955 | N-acetylserotonin O-methyltransferase-like protein; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity; In the N-terminal section; belongs to the maf family | Radical S-adenosyl methionine domain-containing protein 1, mitochondrial; May be involved in porphyrin cofactor biosynthesis; Belongs to the anaerobic coproporphyrinogen-III oxidase family | 0.690 |
| ASMTL | SETD4 | ENSP00000370718 | ENSP00000382163 | N-acetylserotonin O-methyltransferase-like protein; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity; In the N-terminal section; belongs to the maf family | SET domain containing 4 | 0.635 |
| CDK5RAP1 | MOCS1 | ENSP00000217372 | ENSP00000362282 | CDK5 regulatory subunit-associated protein 1; Specifically inhibits CDK5 activation by CDK5R1 | Molybdenum cofactor biosynthesis protein 1; Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5’-GTP to cyclic pyranopterin monophosphate (cPMP). MOCS1A catalyzes the cyclization of GTP to (8S)-3’,8-cyclo-7,8-dihydroguanosine 5’- triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3’,8-cyclo-7,8-dihydroguanosine 5’-triphosphate to cPMP; In the N-terminal section; belongs to the radical SAM superfamily. MoaA family | 0.441 |
| CDK5RAP1 | RSAD1 | ENSP00000217372 | ENSP00000258955 | CDK5 regulatory subunit-associated protein 1; Specifically inhibits CDK5 activation by CDK5R1 | Radical S-adenosyl methionine domain-containing protein 1, mitochondrial; May be involved in porphyrin cofactor biosynthesis; Belongs to the anaerobic coproporphyrinogen-III oxidase family | 0.642 |
| CPOX | FECH | ENSP00000264193 | ENSP00000372326 | Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family | 0.963 |
| CPOX | RSAD1 | ENSP00000264193 | ENSP00000258955 | Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX | Radical S-adenosyl methionine domain-containing protein 1, mitochondrial; May be involved in porphyrin cofactor biosynthesis; Belongs to the anaerobic coproporphyrinogen-III oxidase family | 0.641 |
| FECH | CPOX | ENSP00000372326 | ENSP00000264193 | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family | Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX | 0.963 |
| FECH | RSAD1 | ENSP00000372326 | ENSP00000258955 | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family | Radical S-adenosyl methionine domain-containing protein 1, mitochondrial; May be involved in porphyrin cofactor biosynthesis; Belongs to the anaerobic coproporphyrinogen-III oxidase family | 0.665 |
| METTL10 | ASMTL | ENSP00000357829 | ENSP00000370718 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | N-acetylserotonin O-methyltransferase-like protein; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity; In the N-terminal section; belongs to the maf family | 0.673 |
| METTL10 | METTL9 | ENSP00000357829 | ENSP00000350874 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | Methyltransferase-like protein 9; Methyltransferase like 9 | 0.613 |
| METTL10 | MTRF1L | ENSP00000357829 | ENSP00000356202 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | Peptide chain release factor 1-like, mitochondrial; Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG | 0.566 |
| METTL10 | RRNAD1 | ENSP00000357829 | ENSP00000357199 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | Protein RRNAD1; Ribosomal RNA adenine dimethylase domain containing 1; Belongs to the RRNAD1 family | 0.595 |
| METTL10 | RSAD1 | ENSP00000357829 | ENSP00000258955 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | Radical S-adenosyl methionine domain-containing protein 1, mitochondrial; May be involved in porphyrin cofactor biosynthesis; Belongs to the anaerobic coproporphyrinogen-III oxidase family | 0.624 |
| METTL10 | SETD4 | ENSP00000357829 | ENSP00000382163 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | SET domain containing 4 | 0.670 |
| METTL9 | ASMTL | ENSP00000350874 | ENSP00000370718 | Methyltransferase-like protein 9; Methyltransferase like 9 | N-acetylserotonin O-methyltransferase-like protein; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity; In the N-terminal section; belongs to the maf family | 0.605 |
| METTL9 | METTL10 | ENSP00000350874 | ENSP00000357829 | Methyltransferase-like protein 9; Methyltransferase like 9 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | 0.613 |
