| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATP5B | COX11 | ENSP00000262030 | ENSP00000299335 | ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] | Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Mitochondrial respiratory chain complex assembly factors | 0.686 |
| ATP5B | SLC19A2 | ENSP00000262030 | ENSP00000236137 | ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] | Thiamine transporter 1; High-affinity transporter for the intake of thiamine; Solute carriers | 0.766 |
| ATP5B | SLC19A3 | ENSP00000262030 | ENSP00000258403 | ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] | Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family | 0.576 |
| COX11 | ATP5B | ENSP00000299335 | ENSP00000262030 | Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Mitochondrial respiratory chain complex assembly factors | ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] | 0.686 |
| COX11 | SLC19A2 | ENSP00000299335 | ENSP00000236137 | Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Mitochondrial respiratory chain complex assembly factors | Thiamine transporter 1; High-affinity transporter for the intake of thiamine; Solute carriers | 0.524 |
| COX11 | SLC19A3 | ENSP00000299335 | ENSP00000258403 | Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Mitochondrial respiratory chain complex assembly factors | Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family | 0.629 |
| RFC2 | SLC19A2 | ENSP00000055077 | ENSP00000236137 | Replication factor C subunit 2; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity) | Thiamine transporter 1; High-affinity transporter for the intake of thiamine; Solute carriers | 0.642 |
| RFC2 | SLC19A3 | ENSP00000055077 | ENSP00000258403 | Replication factor C subunit 2; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity) | Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family | 0.655 |
| SLC19A2 | ATP5B | ENSP00000236137 | ENSP00000262030 | Thiamine transporter 1; High-affinity transporter for the intake of thiamine; Solute carriers | ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] | 0.766 |
| SLC19A2 | COX11 | ENSP00000236137 | ENSP00000299335 | Thiamine transporter 1; High-affinity transporter for the intake of thiamine; Solute carriers | Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Mitochondrial respiratory chain complex assembly factors | 0.524 |
| SLC19A2 | RFC2 | ENSP00000236137 | ENSP00000055077 | Thiamine transporter 1; High-affinity transporter for the intake of thiamine; Solute carriers | Replication factor C subunit 2; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity) | 0.642 |
| SLC19A2 | SLC19A3 | ENSP00000236137 | ENSP00000258403 | Thiamine transporter 1; High-affinity transporter for the intake of thiamine; Solute carriers | Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family | 0.811 |
| SLC19A2 | SLC22A15 | ENSP00000236137 | ENSP00000358515 | Thiamine transporter 1; High-affinity transporter for the intake of thiamine; Solute carriers | Solute carrier family 22 member 15; Probably transports organic cations (By similarity). Appears not to be the agmatine transporter; Solute carriers | 0.554 |
| SLC19A2 | THTPA | ENSP00000236137 | ENSP00000288014 | Thiamine transporter 1; High-affinity transporter for the intake of thiamine; Solute carriers | Thiamine-triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP); Belongs to the ThTPase family | 0.570 |
| SLC19A2 | TPK1 | ENSP00000236137 | ENSP00000353165 | Thiamine transporter 1; High-affinity transporter for the intake of thiamine; Solute carriers | Thiamin pyrophosphokinase 1; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate | 0.641 |
| SLC19A3 | ATP5B | ENSP00000258403 | ENSP00000262030 | Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family | ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] | 0.576 |
| SLC19A3 | COX11 | ENSP00000258403 | ENSP00000299335 | Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family | Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Mitochondrial respiratory chain complex assembly factors | 0.629 |
| SLC19A3 | RFC2 | ENSP00000258403 | ENSP00000055077 | Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family | Replication factor C subunit 2; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity) | 0.655 |
| SLC19A3 | SLC19A2 | ENSP00000258403 | ENSP00000236137 | Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family | Thiamine transporter 1; High-affinity transporter for the intake of thiamine; Solute carriers | 0.811 |
| SLC19A3 | SLC22A15 | ENSP00000258403 | ENSP00000358515 | Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family | Solute carrier family 22 member 15; Probably transports organic cations (By similarity). Appears not to be the agmatine transporter; Solute carriers | 0.616 |
