PRRG4 protein (human) - STRING database

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PRRG4

Transmembrane gamma-carboxyglutamic acid protein 4; Proline rich and Gla domain containing (226 aa)

Predicted Functional Partners:

QSER1

0.836

CCDC73

0.669

TCP11L1

0.651

YAP1

0.559

VNN1

0.545

CLEC4D

0.541

DEPDC7

0.533

EHF

0.512

C5orf24

0.509

EIF3M

0.485

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C5orf24	PRRG4	ENSP00000378427	ENSP00000257836	UPF0461 protein C5orf24; Chromosome 5 open reading frame 24; Belongs to the UPF0461 family	Transmembrane gamma-carboxyglutamic acid protein 4; Proline rich and Gla domain containing	0.509
CCDC73	DEPDC7	ENSP00000335325	ENSP00000241051	Coiled-coil domain containing 73	DEP domain containing 7; Belongs to the DEPDC7 family	0.636
CCDC73	EIF3M	ENSP00000335325	ENSP00000436049	Coiled-coil domain containing 73	Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.593
CCDC73	PRRG4	ENSP00000335325	ENSP00000257836	Coiled-coil domain containing 73	Transmembrane gamma-carboxyglutamic acid protein 4; Proline rich and Gla domain containing	0.669
CCDC73	QSER1	ENSP00000335325	ENSP00000382241	Coiled-coil domain containing 73	Glutamine and serine rich 1	0.711
CCDC73	TCP11L1	ENSP00000335325	ENSP00000335595	Coiled-coil domain containing 73	T-complex protein 11-like protein 1; T-complex 11 like 1	0.704
CLEC4D	PRRG4	ENSP00000299665	ENSP00000257836	C-type lectin domain family 4 member D; Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T cells; C-type lectin domain containing	Transmembrane gamma-carboxyglutamic acid protein 4; Proline rich and Gla domain containing	0.541
CLEC4D	VNN1	ENSP00000299665	ENSP00000356905	C-type lectin domain family 4 member D; Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T cells; C-type lectin domain containing	Pantetheinase; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine; Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family	0.464
DEPDC7	CCDC73	ENSP00000241051	ENSP00000335325	DEP domain containing 7; Belongs to the DEPDC7 family	Coiled-coil domain containing 73	0.636
DEPDC7	EIF3M	ENSP00000241051	ENSP00000436049	DEP domain containing 7; Belongs to the DEPDC7 family	Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.904
DEPDC7	PRRG4	ENSP00000241051	ENSP00000257836	DEP domain containing 7; Belongs to the DEPDC7 family	Transmembrane gamma-carboxyglutamic acid protein 4; Proline rich and Gla domain containing	0.533
DEPDC7	QSER1	ENSP00000241051	ENSP00000382241	DEP domain containing 7; Belongs to the DEPDC7 family	Glutamine and serine rich 1	0.606
DEPDC7	TCP11L1	ENSP00000241051	ENSP00000335595	DEP domain containing 7; Belongs to the DEPDC7 family	T-complex protein 11-like protein 1; T-complex 11 like 1	0.661
EHF	PRRG4	ENSP00000435835	ENSP00000257836	ETS homologous factor; Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. May act as a repressor for a specific subset of ETS/AP-1-responsive genes and as a modulator of the nuclear response to mitogen- activated protein kinase signaling cascades. Binds to DNA sequences containing the consensus nucleotide core sequence GGAA. Involved in regulation of TNFRSF10B/DR5 expression through Ets- binding sequences on the TNFRSF10B/DR5 promoter. May contribute to development and carcinogenesis by acting as a tumor suppressor gene or an [...]	Transmembrane gamma-carboxyglutamic acid protein 4; Proline rich and Gla domain containing	0.512
EIF3M	CCDC73	ENSP00000436049	ENSP00000335325	Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	Coiled-coil domain containing 73	0.593
EIF3M	DEPDC7	ENSP00000436049	ENSP00000241051	Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	DEP domain containing 7; Belongs to the DEPDC7 family	0.904
EIF3M	PRRG4	ENSP00000436049	ENSP00000257836	Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	Transmembrane gamma-carboxyglutamic acid protein 4; Proline rich and Gla domain containing	0.485
EIF3M	QSER1	ENSP00000436049	ENSP00000382241	Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	Glutamine and serine rich 1	0.587
EIF3M	TCP11L1	ENSP00000436049	ENSP00000335595	Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	T-complex protein 11-like protein 1; T-complex 11 like 1	0.579
PRRG4	C5orf24	ENSP00000257836	ENSP00000378427	Transmembrane gamma-carboxyglutamic acid protein 4; Proline rich and Gla domain containing	UPF0461 protein C5orf24; Chromosome 5 open reading frame 24; Belongs to the UPF0461 family	0.509

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