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  • 11.0 [archived version]
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TM4SF18 TM4SF18 ZNF292 ZNF292 TMEM121 TMEM121 TMEM200A TMEM200A RALGPS2 RALGPS2 FAM189A2 FAM189A2 C2orf80 C2orf80 TJP2 TJP2 TSPO TSPO BAAT BAAT TMC1 TMC1
"FAM189A2" - Protein FAM189A2 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
FAM189A2Protein FAM189A2; Family with sequence similarity 189 member A2 (450 aa)    
Predicted Functional Partners:
TJP2
Tight junction protein ZO-2; Plays a role in tight junctions and adherens junctions; Belongs to the MAGUK family (1221 aa)
     
   
  0.808
TSPO
Translocator protein; Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides; Belongs to the TspO/BZRP family (169 aa)
           
  0.802
TMEM200A
Transmembrane protein 200A; Belongs to the TMEM200 family (491 aa)
           
  0.783
TMEM121
Transmembrane protein 121; May play a role in MAPK signaling; Belongs to the TMEM121 family (319 aa)
           
  0.770
TMC1
Transmembrane channel-like protein 1; Probable ion channel required for the normal function of cochlear hair cells; Belongs to the TMC family (760 aa)
           
  0.748
C2orf80
Uncharacterized protein C2orf80; Chromosome 2 open reading frame 80 (193 aa)
           
  0.673
RALGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing (583 aa)
           
  0.661
BAAT
Bile acid-CoA-amino acid N-acyltransferase; Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile aci [...] (418 aa)
           
  0.626
TM4SF18
Transmembrane 4 L six family member 18 (201 aa)
     
   
  0.606
ZNF292
Zinc finger protein 292; May be involved in transcriptional regulation; Zinc fingers C2H2-type (2723 aa)
           
  0.578
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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