ADAMDEC1 protein (human) - STRING database

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ADAMDEC1

ADAM DEC1; May play an important role in the control of the immune response and during pregnancy (470 aa)

Predicted Functional Partners:

ZNF511

0.665

CXCL9

0.633

KNDC1

0.622

GPR123

0.604

SLAMF8

0.517

COBLL1

0.513

EML1

0.495

PNMA2

0.488

ERLIN1

0.478

C1QC

0.433

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMDEC1	C1QC	ENSP00000256412	ENSP00000363770	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	Complement C1q subcomponent subunit C; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes	0.433
ADAMDEC1	COBLL1	ENSP00000256412	ENSP00000341360	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	Cordon-bleu WH2 repeat protein like 1	0.513
ADAMDEC1	CXCL9	ENSP00000256412	ENSP00000354901	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	C-X-C motif chemokine 9; Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3; Belongs to the intercrine alpha (chemokine CxC) family	0.633
ADAMDEC1	EML1	ENSP00000256412	ENSP00000334314	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	Echinoderm microtubule-associated protein-like 1; Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se; Belongs to the WD repeat EMAP family	0.495
ADAMDEC1	ERLIN1	ENSP00000256412	ENSP00000410964	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	Erlin-1; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex; Belongs to the band 7/mec-2 family	0.478
ADAMDEC1	GPR123	ENSP00000256412	ENSP00000376384	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	Adhesion G protein-coupled receptor A1; Orphan receptor	0.604
ADAMDEC1	KNDC1	ENSP00000256412	ENSP00000304437	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence	0.622
ADAMDEC1	PNMA2	ENSP00000256412	ENSP00000429344	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	Paraneoplastic Ma antigens; Belongs to the PNMA family	0.488
ADAMDEC1	SLAMF8	ENSP00000256412	ENSP00000289707	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	SLAM family member 8; May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor; CD molecules	0.517
ADAMDEC1	ZNF511	ENSP00000256412	ENSP00000355251	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	Zinc finger protein 511; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.665
C1QC	ADAMDEC1	ENSP00000363770	ENSP00000256412	Complement C1q subcomponent subunit C; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	0.433
C1QC	CXCL9	ENSP00000363770	ENSP00000354901	Complement C1q subcomponent subunit C; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes	C-X-C motif chemokine 9; Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3; Belongs to the intercrine alpha (chemokine CxC) family	0.432
C1QC	SLAMF8	ENSP00000363770	ENSP00000289707	Complement C1q subcomponent subunit C; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes	SLAM family member 8; May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor; CD molecules	0.562
COBLL1	ADAMDEC1	ENSP00000341360	ENSP00000256412	Cordon-bleu WH2 repeat protein like 1	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	0.513
CXCL9	ADAMDEC1	ENSP00000354901	ENSP00000256412	C-X-C motif chemokine 9; Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3; Belongs to the intercrine alpha (chemokine CxC) family	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	0.633
CXCL9	C1QC	ENSP00000354901	ENSP00000363770	C-X-C motif chemokine 9; Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3; Belongs to the intercrine alpha (chemokine CxC) family	Complement C1q subcomponent subunit C; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes	0.432
CXCL9	SLAMF8	ENSP00000354901	ENSP00000289707	C-X-C motif chemokine 9; Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3; Belongs to the intercrine alpha (chemokine CxC) family	SLAM family member 8; May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor; CD molecules	0.559
EML1	ADAMDEC1	ENSP00000334314	ENSP00000256412	Echinoderm microtubule-associated protein-like 1; Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se; Belongs to the WD repeat EMAP family	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	0.495
ERLIN1	ADAMDEC1	ENSP00000410964	ENSP00000256412	Erlin-1; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex; Belongs to the band 7/mec-2 family	ADAM DEC1; May play an important role in the control of the immune response and during pregnancy	0.478
ERLIN1	GPR123	ENSP00000410964	ENSP00000376384	Erlin-1; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex; Belongs to the band 7/mec-2 family	Adhesion G protein-coupled receptor A1; Orphan receptor	0.612

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