| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACY1 | ACY3 | ENSP00000384296 | ENSP00000255082 | Aminoacylase-1; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate); Belongs to the peptidase M20A family | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | 0.671 |
| ACY1 | ASPA | ENSP00000384296 | ENSP00000263080 | Aminoacylase-1; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate); Belongs to the peptidase M20A family | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids | 0.908 |
| ACY1 | OAT | ENSP00000384296 | ENSP00000357838 | Aminoacylase-1; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate); Belongs to the peptidase M20A family | Ornithine aminotransferase, mitochondrial; Ornithine aminotransferase | 0.402 |
| ACY3 | ACY1 | ENSP00000255082 | ENSP00000384296 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | Aminoacylase-1; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate); Belongs to the peptidase M20A family | 0.671 |
| ACY3 | ASPA | ENSP00000255082 | ENSP00000263080 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids | 0.418 |
| ACY3 | GORASP2 | ENSP00000255082 | ENSP00000234160 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | Golgi reassembly-stacking protein 2; Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA; Belongs to the GORASP family | 0.480 |
| ACY3 | LACTB2 | ENSP00000255082 | ENSP00000276590 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | Endoribonuclease LACTB2; Endoribonuclease; cleaves preferentially 3’ to purine- pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3’ -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family | 0.457 |
| ACY3 | OAT | ENSP00000255082 | ENSP00000357838 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | Ornithine aminotransferase, mitochondrial; Ornithine aminotransferase | 0.502 |
| ACY3 | PMM2 | ENSP00000255082 | ENSP00000268261 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | Phosphomannomutase 2; Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions; HAD Asp-based non-protein phosphatases | 0.808 |
| ACY3 | RIMKLA | ENSP00000255082 | ENSP00000414330 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | N-acetylaspartylglutamate synthase A; Catalyzes the synthesis of N-acetyl-L-aspartyl-L- glutamate (NAAG) and N-acetyl-L-aspartyl-L-glutamyl-L-glutamate; Belongs to the RimK family | 0.436 |
| ACY3 | SHPK | ENSP00000255082 | ENSP00000225519 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | Sedoheptulokinase; Acts as a modulator of macrophage activation through control of glucose metabolism | 0.518 |
| ACY3 | SMTNL2 | ENSP00000255082 | ENSP00000373964 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | Smoothelin-like protein 2; Smoothelin like 2 | 0.409 |
| ACY3 | TBX10 | ENSP00000255082 | ENSP00000335191 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | T-box transcription factor TBX10; Probable transcriptional regulator involved in developmental processes; T-boxes | 0.490 |
| ASPA | ACY1 | ENSP00000263080 | ENSP00000384296 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids | Aminoacylase-1; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate); Belongs to the peptidase M20A family | 0.908 |
| ASPA | ACY3 | ENSP00000263080 | ENSP00000255082 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | 0.418 |
| ASPA | OAT | ENSP00000263080 | ENSP00000357838 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids | Ornithine aminotransferase, mitochondrial; Ornithine aminotransferase | 0.453 |
| ASPA | RIMKLA | ENSP00000263080 | ENSP00000414330 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids | N-acetylaspartylglutamate synthase A; Catalyzes the synthesis of N-acetyl-L-aspartyl-L- glutamate (NAAG) and N-acetyl-L-aspartyl-L-glutamyl-L-glutamate; Belongs to the RimK family | 0.925 |
| ASPA | SHPK | ENSP00000263080 | ENSP00000225519 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids | Sedoheptulokinase; Acts as a modulator of macrophage activation through control of glucose metabolism | 0.796 |
| GORASP2 | ACY3 | ENSP00000234160 | ENSP00000255082 | Golgi reassembly-stacking protein 2; Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA; Belongs to the GORASP family | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | 0.480 |
| LACTB2 | ACY3 | ENSP00000276590 | ENSP00000255082 | Endoribonuclease LACTB2; Endoribonuclease; cleaves preferentially 3’ to purine- pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3’ -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity) | 0.457 |
