EEFSEC protein (human) - STRING database

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EEFSEC

Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP (596 aa)

Predicted Functional Partners:

SECISBP2

0.997

RPS3

0.986

RPL30

0.980

RPS6

0.972

RPS20

0.968

RPL7A

0.967

RPS11

0.966

RPS28

0.966

RPS25

0.965

RPL9

0.964

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEFSEC	RPL30	ENSP00000254730	ENSP00000428085	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	0.980
EEFSEC	RPL7A	ENSP00000254730	ENSP00000361076	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein L7a	0.967
EEFSEC	RPL9	ENSP00000254730	ENSP00000400467	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	L ribosomal proteins	0.964
EEFSEC	RPS11	ENSP00000254730	ENSP00000270625	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family	0.966
EEFSEC	RPS20	ENSP00000254730	ENSP00000429374	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein S20	0.968
EEFSEC	RPS25	ENSP00000254730	ENSP00000435096	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein S25	0.965
EEFSEC	RPS28	ENSP00000254730	ENSP00000472469	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family	0.966
EEFSEC	RPS3	ENSP00000254730	ENSP00000278572	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protein [...]	0.986
EEFSEC	RPS6	ENSP00000254730	ENSP00000369757	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA; S ribosomal proteins	0.972
EEFSEC	SECISBP2	ENSP00000254730	ENSP00000364965	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Selenocysteine insertion sequence-binding protein 2; Binds to the SECIS element in the 3’-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB	0.997
RPL30	EEFSEC	ENSP00000428085	ENSP00000254730	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	0.980
RPL30	RPL7A	ENSP00000428085	ENSP00000361076	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	Ribosomal protein L7a	0.999
RPL30	RPL9	ENSP00000428085	ENSP00000400467	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	L ribosomal proteins	0.999
RPL30	RPS11	ENSP00000428085	ENSP00000270625	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family	0.999
RPL30	RPS20	ENSP00000428085	ENSP00000429374	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	Ribosomal protein S20	0.999
RPL30	RPS25	ENSP00000428085	ENSP00000435096	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	Ribosomal protein S25	0.999
RPL30	RPS28	ENSP00000428085	ENSP00000472469	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family	0.999
RPL30	RPS3	ENSP00000428085	ENSP00000278572	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protein [...]	0.999
RPL30	RPS6	ENSP00000428085	ENSP00000369757	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA; S ribosomal proteins	0.999
RPL30	SECISBP2	ENSP00000428085	ENSP00000364965	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	Selenocysteine insertion sequence-binding protein 2; Binds to the SECIS element in the 3’-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB	0.979

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