node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDR2L | CLIC2 | ENSP00000336587 | ENSP00000358460 | Cerebellar degeneration related protein 2 like | Chloride intracellular channel protein 2; Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx | 0.463 |
CDR2L | CMTM8 | ENSP00000336587 | ENSP00000307741 | Cerebellar degeneration related protein 2 like | CKLF like MARVEL transmembrane domain containing 8; Belongs to the chemokine-like factor family | 0.562 |
CDR2L | EMILIN2 | ENSP00000336587 | ENSP00000254528 | Cerebellar degeneration related protein 2 like | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | 0.692 |
CLIC2 | CDR2L | ENSP00000358460 | ENSP00000336587 | Chloride intracellular channel protein 2; Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx | Cerebellar degeneration related protein 2 like | 0.463 |
CLIC2 | EMILIN2 | ENSP00000358460 | ENSP00000254528 | Chloride intracellular channel protein 2; Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | 0.493 |
CLUL1 | EMILIN2 | ENSP00000441726 | ENSP00000254528 | Clusterin-like protein 1; Clusterin like 1 | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | 0.648 |
CLUL1 | LPIN2 | ENSP00000441726 | ENSP00000261596 | Clusterin-like protein 1; Clusterin like 1 | Phosphatidate phosphatase LPIN2; Plays important roles in controlling the metabolism of fatty acids at different levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism (By similarity); Lipins | 0.556 |
CLUL1 | MYOM1 | ENSP00000441726 | ENSP00000348821 | Clusterin-like protein 1; Clusterin like 1 | Myomesin-1; Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent; Fibronectin type III domain containing | 0.588 |
CMTM8 | CDR2L | ENSP00000307741 | ENSP00000336587 | CKLF like MARVEL transmembrane domain containing 8; Belongs to the chemokine-like factor family | Cerebellar degeneration related protein 2 like | 0.562 |
CMTM8 | EMILIN2 | ENSP00000307741 | ENSP00000254528 | CKLF like MARVEL transmembrane domain containing 8; Belongs to the chemokine-like factor family | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | 0.572 |
EMILIN1 | EMILIN2 | ENSP00000369677 | ENSP00000254528 | EMILIN-1; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | 0.487 |
EMILIN2 | CDR2L | ENSP00000254528 | ENSP00000336587 | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | Cerebellar degeneration related protein 2 like | 0.692 |
EMILIN2 | CLIC2 | ENSP00000254528 | ENSP00000358460 | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | Chloride intracellular channel protein 2; Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx | 0.493 |
EMILIN2 | CLUL1 | ENSP00000254528 | ENSP00000441726 | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | Clusterin-like protein 1; Clusterin like 1 | 0.648 |
EMILIN2 | CMTM8 | ENSP00000254528 | ENSP00000307741 | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | CKLF like MARVEL transmembrane domain containing 8; Belongs to the chemokine-like factor family | 0.572 |
EMILIN2 | EMILIN1 | ENSP00000254528 | ENSP00000369677 | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | EMILIN-1; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | 0.487 |
EMILIN2 | LPIN2 | ENSP00000254528 | ENSP00000261596 | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | Phosphatidate phosphatase LPIN2; Plays important roles in controlling the metabolism of fatty acids at different levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism (By similarity); Lipins | 0.456 |
EMILIN2 | MYOM1 | ENSP00000254528 | ENSP00000348821 | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | Myomesin-1; Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent; Fibronectin type III domain containing | 0.559 |
EMILIN2 | RAB42 | ENSP00000254528 | ENSP00000362932 | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | Ras-related protein Rab-42; RAB42, member RAS oncogene family | 0.440 |
EMILIN2 | RMND5A | ENSP00000254528 | ENSP00000283632 | EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity; EMI domain containing | Protein RMD5 homolog A; Required for meiotic nuclear division 5 homolog A; CTLH complex | 0.542 |