node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASB8 | ZNF132 | ENSP00000320893 | ENSP00000254166 | Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Ankyrin repeat domain containing | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.468 |
EPN1 | ZNF132 | ENSP00000406209 | ENSP00000254166 | Epsin-1; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis; Belongs to the epsin family | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.408 |
FBXO39 | PCDHB2 | ENSP00000321386 | ENSP00000194155 | F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | Protocadherin beta-2; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins | 0.451 |
FBXO39 | ZNF132 | ENSP00000321386 | ENSP00000254166 | F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.474 |
HTN3 | ZNF132 | ENSP00000432561 | ENSP00000254166 | Histatin-3; Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9 | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.577 |
KCNJ14 | SLC27A5 | ENSP00000375756 | ENSP00000263093 | ATP-sensitive inward rectifier potassium channel 14; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium [...] | Bile acyl-CoA synthetase; Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol; Belongs to the ATP-dependent AMP-binding enzyme family | 0.412 |
KCNJ14 | ZNF132 | ENSP00000375756 | ENSP00000254166 | ATP-sensitive inward rectifier potassium channel 14; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium [...] | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.571 |
NKG7 | ZNF132 | ENSP00000221978 | ENSP00000254166 | Protein NKG7; Natural killer cell granule protein 7; Belongs to the PMP-22/EMP/MP20 family | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.476 |
PCDHB2 | FBXO39 | ENSP00000194155 | ENSP00000321386 | Protocadherin beta-2; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins | F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | 0.451 |
PCDHB2 | ZNF132 | ENSP00000194155 | ENSP00000254166 | Protocadherin beta-2; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.404 |
RPL28 | ZNF132 | ENSP00000452909 | ENSP00000254166 | 60S ribosomal protein L28; Component of the large ribosomal subunit; Belongs to the eukaryotic ribosomal protein eL28 family | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.449 |
SLC27A5 | KCNJ14 | ENSP00000263093 | ENSP00000375756 | Bile acyl-CoA synthetase; Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol; Belongs to the ATP-dependent AMP-binding enzyme family | ATP-sensitive inward rectifier potassium channel 14; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium [...] | 0.412 |
SLC27A5 | ZNF132 | ENSP00000263093 | ENSP00000254166 | Bile acyl-CoA synthetase; Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol; Belongs to the ATP-dependent AMP-binding enzyme family | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.655 |
YIPF2 | ZNF132 | ENSP00000253031 | ENSP00000254166 | Protein YIPF2; Yip1 domain family member 2 | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.548 |
ZNF132 | ASB8 | ENSP00000254166 | ENSP00000320893 | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Ankyrin repeat domain containing | 0.468 |
ZNF132 | EPN1 | ENSP00000254166 | ENSP00000406209 | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Epsin-1; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis; Belongs to the epsin family | 0.408 |
ZNF132 | FBXO39 | ENSP00000254166 | ENSP00000321386 | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | 0.474 |
ZNF132 | HTN3 | ENSP00000254166 | ENSP00000432561 | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Histatin-3; Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9 | 0.577 |
ZNF132 | KCNJ14 | ENSP00000254166 | ENSP00000375756 | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | ATP-sensitive inward rectifier potassium channel 14; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium [...] | 0.571 |
ZNF132 | NKG7 | ENSP00000254166 | ENSP00000221978 | Zinc finger protein 132; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Protein NKG7; Natural killer cell granule protein 7; Belongs to the PMP-22/EMP/MP20 family | 0.476 |