node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAALC | ZNF236 | ENSP00000312457 | ENSP00000253159 | Brain and acute leukemia, cytoplasmic; BAALC, MAP3K1 and KLF4 binding | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.537 |
CT47B1 | ZNF236 | ENSP00000360360 | ENSP00000253159 | Cancer/testis antigen family 47, member B1 | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.440 |
DHX8 | TPST2 | ENSP00000262415 | ENSP00000339813 | ATP-dependent RNA helicase DHX8; Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome; Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily | Protein-tyrosine sulfotransferase 2; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3’-phosphoadenylyl sulfate (PAPS) as cosubstrate; Sulfotransferases, membrane bound | 0.478 |
DHX8 | ZNF236 | ENSP00000262415 | ENSP00000253159 | ATP-dependent RNA helicase DHX8; Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome; Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.446 |
EPHB2 | TPST2 | ENSP00000363763 | ENSP00000339813 | Ephrin type-B receptor 2; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral corte [...] | Protein-tyrosine sulfotransferase 2; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3’-phosphoadenylyl sulfate (PAPS) as cosubstrate; Sulfotransferases, membrane bound | 0.437 |
EPHB2 | ZNF236 | ENSP00000363763 | ENSP00000253159 | Ephrin type-B receptor 2; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral corte [...] | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.512 |
GALR1 | ZNF236 | ENSP00000299727 | ENSP00000253159 | Galanin receptor type 1; Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity; Belongs to the G-protein coupled receptor 1 family | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.541 |
HNRNPUL1 | KHDRBS1 | ENSP00000375863 | ENSP00000313829 | Heterogeneous nuclear ribonucleoprotein U-like protein 1; Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand- stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro | KH domain-containing, RNA-binding, signal transduction-associated protein 1; Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain- containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediate [...] | 0.525 |
HNRNPUL1 | ZNF236 | ENSP00000375863 | ENSP00000253159 | Heterogeneous nuclear ribonucleoprotein U-like protein 1; Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand- stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.493 |
KHDRBS1 | HNRNPUL1 | ENSP00000313829 | ENSP00000375863 | KH domain-containing, RNA-binding, signal transduction-associated protein 1; Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain- containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediate [...] | Heterogeneous nuclear ribonucleoprotein U-like protein 1; Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand- stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro | 0.525 |
KHDRBS1 | ZNF236 | ENSP00000313829 | ENSP00000253159 | KH domain-containing, RNA-binding, signal transduction-associated protein 1; Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain- containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediate [...] | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.445 |
MLLT3 | ZNF236 | ENSP00000369695 | ENSP00000253159 | Protein AF-9; Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically recognizes and binds acylated histone H3, with a marked preference for histone H3 that is crotonylated. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. Recognizes and binds histone H3 crotonylated at ’Lys-9’ (H3K9cr), and with slightly lower affinity histone H3 crotonylate [...] | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.441 |
TPST2 | DHX8 | ENSP00000339813 | ENSP00000262415 | Protein-tyrosine sulfotransferase 2; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3’-phosphoadenylyl sulfate (PAPS) as cosubstrate; Sulfotransferases, membrane bound | ATP-dependent RNA helicase DHX8; Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome; Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily | 0.478 |
TPST2 | EPHB2 | ENSP00000339813 | ENSP00000363763 | Protein-tyrosine sulfotransferase 2; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3’-phosphoadenylyl sulfate (PAPS) as cosubstrate; Sulfotransferases, membrane bound | Ephrin type-B receptor 2; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral corte [...] | 0.437 |
TPST2 | ZNF236 | ENSP00000339813 | ENSP00000253159 | Protein-tyrosine sulfotransferase 2; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3’-phosphoadenylyl sulfate (PAPS) as cosubstrate; Sulfotransferases, membrane bound | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.564 |
ZADH2 | ZNF236 | ENSP00000323678 | ENSP00000253159 | Prostaglandin reductase 3; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest efficienty towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.509 |
ZNF236 | BAALC | ENSP00000253159 | ENSP00000312457 | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | Brain and acute leukemia, cytoplasmic; BAALC, MAP3K1 and KLF4 binding | 0.537 |
ZNF236 | CT47B1 | ENSP00000253159 | ENSP00000360360 | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | Cancer/testis antigen family 47, member B1 | 0.440 |
ZNF236 | DHX8 | ENSP00000253159 | ENSP00000262415 | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | ATP-dependent RNA helicase DHX8; Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome; Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily | 0.446 |
ZNF236 | EPHB2 | ENSP00000253159 | ENSP00000363763 | Zinc finger protein 236; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | Ephrin type-B receptor 2; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral corte [...] | 0.512 |