• Version:
  • 11.0 [archived version]
STRINGSTRING
EN1 EN1 EVX1 EVX1 PRDM11 PRDM11 PRDM12 PRDM12 DBX1 DBX1 FNDC3A FNDC3A HMCN2 HMCN2 NUP35 NUP35 DBX2 DBX2 OR11L1 OR11L1 OR6F1 OR6F1
"PRDM12" - PR domain zinc finger protein 12 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM12PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; PR/SET domain family (367 aa)    
Predicted Functional Partners:
PRDM11
PR domain-containing protein 11; May be involved in transcription regulation; Belongs to the class V-like SAM-binding methyltransferase superfamily (1177 aa)
            
  0.750
EVX1
Homeobox even-skipped homolog protein 1; May play a role in the specification of neuronal cell types; HOXL subclass homeoboxes (407 aa)
            
  0.652
OR11L1
Olfactory receptor 11L1; Odorant receptor; Olfactory receptors, family 11 (322 aa)
            
  0.577
FNDC3A
Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family (1198 aa)
            
  0.571
OR6F1
Olfactory receptor 6F1; Odorant receptor; Olfactory receptors, family 6 (308 aa)
            
  0.566
HMCN2
Hemicentin-2; Immunoglobulin like domain containing; Fibulins (5059 aa)
            
  0.564
DBX1
Homeobox protein DBX1; Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity); NKL subclass homeoboxes and pseudogenes (343 aa)
      
   
  0.555
EN1
Homeobox protein engrailed-1; NKL subclass homeoboxes and pseudogenes (392 aa)
      
   
  0.541
DBX2
Homeobox protein DBX2; NKL subclass homeoboxes and pseudogenes (339 aa)
            
  0.513
NUP35
Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs). Can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC (326 aa)
            
  0.511
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >