ZSWIM6 protein (human) - STRING database

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Score

ZSWIM6

Zinc finger SWIM-type containing 6 (1215 aa)

Predicted Functional Partners:

ALX1

0.812

ALX3

0.810

ALX4

0.629

MIER3

0.580

HDGFL1

0.577

KATNB1

0.516

CCDC15

0.513

ZNF532

0.497

WDPCP

0.493

ST8SIA3

0.486

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALX1	ALX4	ENSP00000315417	ENSP00000332744	ALX homeobox protein 1; Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1; Belongs to the paired homeobox family	Homeobox protein aristaless-like 4; Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development; Belongs to the paired homeobox family	0.461
ALX1	ZSWIM6	ENSP00000315417	ENSP00000252744	ALX homeobox protein 1; Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1; Belongs to the paired homeobox family	Zinc finger SWIM-type containing 6	0.812
ALX3	ZSWIM6	ENSP00000358807	ENSP00000252744	Homeobox protein aristaless-like 3; Transcriptional regulator with a possible role in patterning of mesoderm during development; PRD class homeoboxes and pseudogenes	Zinc finger SWIM-type containing 6	0.810
ALX4	ALX1	ENSP00000332744	ENSP00000315417	Homeobox protein aristaless-like 4; Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development; Belongs to the paired homeobox family	ALX homeobox protein 1; Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1; Belongs to the paired homeobox family	0.461
ALX4	ZSWIM6	ENSP00000332744	ENSP00000252744	Homeobox protein aristaless-like 4; Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development; Belongs to the paired homeobox family	Zinc finger SWIM-type containing 6	0.629
CCDC15	ZSWIM6	ENSP00000341684	ENSP00000252744	Coiled-coil domain containing 15	Zinc finger SWIM-type containing 6	0.513
HDGFL1	ZSWIM6	ENSP00000442129	ENSP00000252744	Hepatoma-derived growth factor-like protein 1; Heparin binding growth factor family; Belongs to the HDGF family	Zinc finger SWIM-type containing 6	0.577
KATNB1	WDPCP	ENSP00000368982	ENSP00000272321	Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...]	WD repeat-containing and planar cell polarity effector protein fritz homolog; Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity); Bardet-Biedl syndrome associated	0.552
KATNB1	ZSWIM6	ENSP00000368982	ENSP00000252744	Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...]	Zinc finger SWIM-type containing 6	0.516
MIER3	ST8SIA3	ENSP00000370596	ENSP00000320431	Mesoderm induction early response protein 3; Transcriptional repressor; Myb/SANT domain containing	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R-alpha 2,8-sialyltransferase; Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages. Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. Displays preference for substrates with alpha-2,3-linked terminal sialic acid. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid; Belongs to the glycosyltransferase 29 family	0.557
MIER3	ZNF532	ENSP00000370596	ENSP00000338217	Mesoderm induction early response protein 3; Transcriptional repressor; Myb/SANT domain containing	Zinc finger protein 532; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.474
MIER3	ZSWIM6	ENSP00000370596	ENSP00000252744	Mesoderm induction early response protein 3; Transcriptional repressor; Myb/SANT domain containing	Zinc finger SWIM-type containing 6	0.580
ST8SIA3	MIER3	ENSP00000320431	ENSP00000370596	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R-alpha 2,8-sialyltransferase; Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages. Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. Displays preference for substrates with alpha-2,3-linked terminal sialic acid. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid; Belongs to the glycosyltransferase 29 family	Mesoderm induction early response protein 3; Transcriptional repressor; Myb/SANT domain containing	0.557
ST8SIA3	ZSWIM6	ENSP00000320431	ENSP00000252744	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R-alpha 2,8-sialyltransferase; Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages. Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. Displays preference for substrates with alpha-2,3-linked terminal sialic acid. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid; Belongs to the glycosyltransferase 29 family	Zinc finger SWIM-type containing 6	0.486
WDPCP	KATNB1	ENSP00000272321	ENSP00000368982	WD repeat-containing and planar cell polarity effector protein fritz homolog; Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity); Bardet-Biedl syndrome associated	Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...]	0.552
WDPCP	ZSWIM6	ENSP00000272321	ENSP00000252744	WD repeat-containing and planar cell polarity effector protein fritz homolog; Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity); Bardet-Biedl syndrome associated	Zinc finger SWIM-type containing 6	0.493
ZNF532	MIER3	ENSP00000338217	ENSP00000370596	Zinc finger protein 532; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Mesoderm induction early response protein 3; Transcriptional repressor; Myb/SANT domain containing	0.474
ZNF532	ZSWIM6	ENSP00000338217	ENSP00000252744	Zinc finger protein 532; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Zinc finger SWIM-type containing 6	0.497
ZSWIM6	ALX1	ENSP00000252744	ENSP00000315417	Zinc finger SWIM-type containing 6	ALX homeobox protein 1; Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1; Belongs to the paired homeobox family	0.812
ZSWIM6	ALX3	ENSP00000252744	ENSP00000358807	Zinc finger SWIM-type containing 6	Homeobox protein aristaless-like 3; Transcriptional regulator with a possible role in patterning of mesoderm during development; PRD class homeoboxes and pseudogenes	0.810

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