ALLC protein (human) - STRING database

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Score

ALLC

Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals (391 aa)

Predicted Functional Partners:

ARMC3

0.629

ALX1

0.626

VPS53

0.617

AGXT

0.591

WDR4

0.570

UNC119

0.561

CNNM1

0.557

WRB

0.545

CLEC3A

0.543

PTPN5

0.537

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGXT	ALLC	ENSP00000302620	ENSP00000252505	Alanine-glyoxylate aminotransferase	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	0.591
ALLC	AGXT	ENSP00000252505	ENSP00000302620	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	Alanine-glyoxylate aminotransferase	0.591
ALLC	ALX1	ENSP00000252505	ENSP00000315417	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	ALX homeobox protein 1; Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1; Belongs to the paired homeobox family	0.626
ALLC	ARMC3	ENSP00000252505	ENSP00000298032	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	Armadillo repeat containing 3	0.629
ALLC	CLEC3A	ENSP00000252505	ENSP00000299642	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin; C-type lectin domain containing	0.543
ALLC	CNNM1	ENSP00000252505	ENSP00000349147	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family	0.557
ALLC	PTPN5	ENSP00000252505	ENSP00000351342	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	Tyrosine-protein phosphatase non-receptor type 5; May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors; Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily	0.537
ALLC	UNC119	ENSP00000252505	ENSP00000337040	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	Protein unc-119 homolog A; Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid- binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Prob [...]	0.561
ALLC	VPS53	ENSP00000252505	ENSP00000401435	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	Vacuolar protein sorting-associated protein 53 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized tr [...]	0.617
ALLC	WDR4	ENSP00000252505	ENSP00000381266	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit; Belongs to the WD repeat TRM82 family	0.570
ALLC	WRB	ENSP00000252505	ENSP00000327716	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	Tail-anchored protein insertion receptor WRB; Receptor for ASNA1/TRC40-mediated insertion of tail- anchored (TA) proteins into the ER membrane; Belongs to the WRB/GET1 family	0.545
ALX1	ALLC	ENSP00000315417	ENSP00000252505	ALX homeobox protein 1; Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1; Belongs to the paired homeobox family	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	0.626
ARMC3	ALLC	ENSP00000298032	ENSP00000252505	Armadillo repeat containing 3	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	0.629
CLEC3A	ALLC	ENSP00000299642	ENSP00000252505	C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin; C-type lectin domain containing	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	0.543
CNNM1	ALLC	ENSP00000349147	ENSP00000252505	Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	0.557
PTPN5	ALLC	ENSP00000351342	ENSP00000252505	Tyrosine-protein phosphatase non-receptor type 5; May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors; Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	0.537
UNC119	ALLC	ENSP00000337040	ENSP00000252505	Protein unc-119 homolog A; Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid- binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Prob [...]	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	0.561
VPS53	ALLC	ENSP00000401435	ENSP00000252505	Vacuolar protein sorting-associated protein 53 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized tr [...]	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	0.617
WDR4	ALLC	ENSP00000381266	ENSP00000252505	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit; Belongs to the WD repeat TRM82 family	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	0.570
WRB	ALLC	ENSP00000327716	ENSP00000252505	Tail-anchored protein insertion receptor WRB; Receptor for ASNA1/TRC40-mediated insertion of tail- anchored (TA) proteins into the ER membrane; Belongs to the WRB/GET1 family	Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals	0.545

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