node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTR10 | ACTR2 | ENSP00000254286 | ENSP00000367220 | Actin related protein 10 homolog; Belongs to the actin family | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | 0.948 |
ACTR10 | ACTR3C | ENSP00000254286 | ENSP00000252071 | Actin related protein 10 homolog; Belongs to the actin family | Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins | 0.810 |
ACTR10 | ARPC3 | ENSP00000254286 | ENSP00000228825 | Actin related protein 10 homolog; Belongs to the actin family | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the ARPC3 family | 0.481 |
ACTR10 | WASL | ENSP00000254286 | ENSP00000223023 | Actin related protein 10 homolog; Belongs to the actin family | Neural Wiskott-Aldrich syndrome protein; Regulates actin polymerization by stimulating the actin- nucleating activity of the Arp2/3 complex. Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression. Plays a role in dendrite spine morphogenesis (By similarity); Wiskott-Aldrich Syndrome protein family | 0.413 |
ACTR2 | ACTR10 | ENSP00000367220 | ENSP00000254286 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Actin related protein 10 homolog; Belongs to the actin family | 0.948 |
ACTR2 | ACTR3C | ENSP00000367220 | ENSP00000252071 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins | 0.886 |
ACTR2 | ARPC1A | ENSP00000367220 | ENSP00000262942 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Actin-related protein 2/3 complex subunit 1A; Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family | 0.999 |
ACTR2 | ARPC1B | ENSP00000367220 | ENSP00000389631 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Actin-related protein 2/3 complex subunit 1B; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family | 0.999 |
ACTR2 | ARPC2 | ENSP00000367220 | ENSP00000295685 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Actin-related protein 2/3 complex subunit 2; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC2 family | 0.999 |
ACTR2 | ARPC3 | ENSP00000367220 | ENSP00000228825 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the ARPC3 family | 0.999 |
ACTR2 | ARPC4 | ENSP00000367220 | ENSP00000388169 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament | 0.999 |
ACTR2 | ARPC5 | ENSP00000367220 | ENSP00000294742 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks | 0.999 |
ACTR2 | ARPC5L | ENSP00000367220 | ENSP00000345361 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Actin-related protein 2/3 complex subunit 5-like protein; May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the ARPC5 family | 0.999 |
ACTR2 | WASL | ENSP00000367220 | ENSP00000223023 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Neural Wiskott-Aldrich syndrome protein; Regulates actin polymerization by stimulating the actin- nucleating activity of the Arp2/3 complex. Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression. Plays a role in dendrite spine morphogenesis (By similarity); Wiskott-Aldrich Syndrome protein family | 0.997 |
ACTR3C | ACTR10 | ENSP00000252071 | ENSP00000254286 | Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins | Actin related protein 10 homolog; Belongs to the actin family | 0.810 |
ACTR3C | ACTR2 | ENSP00000252071 | ENSP00000367220 | Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | 0.886 |
ACTR3C | ARPC1A | ENSP00000252071 | ENSP00000262942 | Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins | Actin-related protein 2/3 complex subunit 1A; Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family | 0.884 |
ACTR3C | ARPC1B | ENSP00000252071 | ENSP00000389631 | Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins | Actin-related protein 2/3 complex subunit 1B; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family | 0.875 |
ACTR3C | ARPC2 | ENSP00000252071 | ENSP00000295685 | Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins | Actin-related protein 2/3 complex subunit 2; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC2 family | 0.906 |
ACTR3C | ARPC3 | ENSP00000252071 | ENSP00000228825 | Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the ARPC3 family | 0.916 |