| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BUD31 | CDC5L | ENSP00000386023 | ENSP00000360532 | Protein BUD31 homolog; Spliceosomal Bact complex | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing | 0.998 |
| BUD31 | DDX49 | ENSP00000386023 | ENSP00000247003 | Protein BUD31 homolog; Spliceosomal Bact complex | Probable ATP-dependent RNA helicase DDX49; DEAD-box helicase 49; Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily | 0.519 |
| BUD31 | DHX40 | ENSP00000386023 | ENSP00000251241 | Protein BUD31 homolog; Spliceosomal Bact complex | Probable ATP-dependent RNA helicase DHX40; Probable ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DEAH subfamily | 0.714 |
| BUD31 | EFTUD2 | ENSP00000386023 | ENSP00000392094 | Protein BUD31 homolog; Spliceosomal Bact complex | 116 kDa U5 small nuclear ribonucleoprotein component; Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily | 0.999 |
| BUD31 | PRPF19 | ENSP00000386023 | ENSP00000227524 | Protein BUD31 homolog; Spliceosomal Bact complex | Pre-mRNA-processing factor 19; Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates ’Lys-63’-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex. Recruite [...] | 0.999 |
| CDC5L | BUD31 | ENSP00000360532 | ENSP00000386023 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing | Protein BUD31 homolog; Spliceosomal Bact complex | 0.998 |
| CDC5L | DDX49 | ENSP00000360532 | ENSP00000247003 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing | Probable ATP-dependent RNA helicase DDX49; DEAD-box helicase 49; Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily | 0.407 |
| CDC5L | DHX40 | ENSP00000360532 | ENSP00000251241 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing | Probable ATP-dependent RNA helicase DHX40; Probable ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DEAH subfamily | 0.731 |
| CDC5L | EFTUD2 | ENSP00000360532 | ENSP00000392094 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing | 116 kDa U5 small nuclear ribonucleoprotein component; Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily | 0.999 |
| CDC5L | PRPF19 | ENSP00000360532 | ENSP00000227524 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing | Pre-mRNA-processing factor 19; Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates ’Lys-63’-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex. Recruite [...] | 0.999 |
| DDX49 | BUD31 | ENSP00000247003 | ENSP00000386023 | Probable ATP-dependent RNA helicase DDX49; DEAD-box helicase 49; Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily | Protein BUD31 homolog; Spliceosomal Bact complex | 0.519 |
| DDX49 | CDC5L | ENSP00000247003 | ENSP00000360532 | Probable ATP-dependent RNA helicase DDX49; DEAD-box helicase 49; Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing | 0.407 |
| DDX49 | DDX54 | ENSP00000247003 | ENSP00000323858 | Probable ATP-dependent RNA helicase DDX49; DEAD-box helicase 49; Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily | ATP-dependent RNA helicase DDX54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors; DEAD-box helicases | 0.943 |
| DDX49 | DHX40 | ENSP00000247003 | ENSP00000251241 | Probable ATP-dependent RNA helicase DDX49; DEAD-box helicase 49; Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily | Probable ATP-dependent RNA helicase DHX40; Probable ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DEAH subfamily | 0.840 |
| DDX49 | EFTUD2 | ENSP00000247003 | ENSP00000392094 | Probable ATP-dependent RNA helicase DDX49; DEAD-box helicase 49; Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily | 116 kDa U5 small nuclear ribonucleoprotein component; Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily | 0.922 |
| DDX49 | PRPF19 | ENSP00000247003 | ENSP00000227524 | Probable ATP-dependent RNA helicase DDX49; DEAD-box helicase 49; Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily | Pre-mRNA-processing factor 19; Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates ’Lys-63’-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex. Recruite [...] | 0.451 |
| DDX54 | DDX49 | ENSP00000323858 | ENSP00000247003 | ATP-dependent RNA helicase DDX54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors; DEAD-box helicases | Probable ATP-dependent RNA helicase DDX49; DEAD-box helicase 49; Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily | 0.943 |
| DDX54 | DHX40 | ENSP00000323858 | ENSP00000251241 | ATP-dependent RNA helicase DDX54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors; DEAD-box helicases | Probable ATP-dependent RNA helicase DHX40; Probable ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DEAH subfamily | 0.708 |
| DDX54 | PRPF19 | ENSP00000323858 | ENSP00000227524 | ATP-dependent RNA helicase DDX54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors; DEAD-box helicases | Pre-mRNA-processing factor 19; Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates ’Lys-63’-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex. Recruite [...] | 0.470 |
| DHX40 | BUD31 | ENSP00000251241 | ENSP00000386023 | Probable ATP-dependent RNA helicase DHX40; Probable ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DEAH subfamily | Protein BUD31 homolog; Spliceosomal Bact complex | 0.714 |
