SEC14L5 protein (human) - STRING database

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Score

SEC14L5

SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing (696 aa)

Predicted Functional Partners:

ALG1

0.911

SESTD1

0.625

PITPNB

0.606

PITPNA

0.594

PRSS33

0.574

ZNF449

0.526

C2orf80

0.516

PSMC6

0.516

PRRC2B

0.512

HYKK

0.511

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALG1	SEC14L5	ENSP00000262374	ENSP00000251170	Chitobiosyldiphosphodolichol beta-mannosyltransferase; Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	0.911
C2orf80	SEC14L5	ENSP00000343171	ENSP00000251170	Uncharacterized protein C2orf80; Chromosome 2 open reading frame 80	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	0.516
HYKK	SEC14L5	ENSP00000455459	ENSP00000251170	Hydroxylysine kinase; Catalyzes the GTP-dependent phosphorylation of 5- hydroxy-L-lysine	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	0.511
PITPNA	SEC14L5	ENSP00000316809	ENSP00000251170	Phosphatidylinositol transfer protein alpha isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	0.594
PITPNB	SEC14L5	ENSP00000321266	ENSP00000251170	Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	0.606
PRRC2B	SEC14L5	ENSP00000349856	ENSP00000251170	Protein PRRC2B; Proline rich coiled-coil 2B	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	0.512
PRRC2B	ZNF449	ENSP00000349856	ENSP00000339585	Protein PRRC2B; Proline rich coiled-coil 2B	Zinc finger protein 449; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.484
PRSS33	SEC14L5	ENSP00000293851	ENSP00000251170	Serine protease 33; Serine protease that has amidolytic activity, cleaving its substrates before Arg residues	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	0.574
PSMC6	SEC14L5	ENSP00000401802	ENSP00000251170	26S proteasome regulatory subunit 10B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated wi [...]	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	0.516
SEC14L5	ALG1	ENSP00000251170	ENSP00000262374	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	Chitobiosyldiphosphodolichol beta-mannosyltransferase; Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily	0.911
SEC14L5	C2orf80	ENSP00000251170	ENSP00000343171	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	Uncharacterized protein C2orf80; Chromosome 2 open reading frame 80	0.516
SEC14L5	HYKK	ENSP00000251170	ENSP00000455459	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	Hydroxylysine kinase; Catalyzes the GTP-dependent phosphorylation of 5- hydroxy-L-lysine	0.511
SEC14L5	PITPNA	ENSP00000251170	ENSP00000316809	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	Phosphatidylinositol transfer protein alpha isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins	0.594
SEC14L5	PITPNB	ENSP00000251170	ENSP00000321266	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins	0.606
SEC14L5	PRRC2B	ENSP00000251170	ENSP00000349856	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	Protein PRRC2B; Proline rich coiled-coil 2B	0.512
SEC14L5	PRSS33	ENSP00000251170	ENSP00000293851	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	Serine protease 33; Serine protease that has amidolytic activity, cleaving its substrates before Arg residues	0.574
SEC14L5	PSMC6	ENSP00000251170	ENSP00000401802	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	26S proteasome regulatory subunit 10B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated wi [...]	0.516
SEC14L5	SESTD1	ENSP00000251170	ENSP00000415332	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	SEC14 domain and spectrin repeat-containing protein 1; May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1	0.625
SEC14L5	ZNF449	ENSP00000251170	ENSP00000339585	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	Zinc finger protein 449; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.526
SESTD1	SEC14L5	ENSP00000415332	ENSP00000251170	SEC14 domain and spectrin repeat-containing protein 1; May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1	SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing	0.625

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