• Version:
  • 11.0 [archived version]
STRINGSTRING
RCBTB1 RCBTB1 TMEM74 TMEM74 SLC43A2 SLC43A2 MLNR MLNR CDADC1 CDADC1 LPAR6 LPAR6 CDA CDA DCTD DCTD TYMS TYMS RFC4 RFC4 SYT14 SYT14
"CDADC1" - Cytidine and dCMP deaminase domain-containing protein 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDADC1Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis; Belongs to the cytidine and deoxycytidylate deaminase family (514 aa)    
Predicted Functional Partners:
TYMS
Thymidylate synthase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (313 aa)
   
 
  0.720
DCTD
Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase (189 aa)
           
  0.708
MLNR
Motilin receptor; Receptor for motilin; Belongs to the G-protein coupled receptor 1 family (412 aa)
           
  0.699
SLC43A2
Large neutral amino acids transporter small subunit 4; Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids; Belongs to the SLC43A transporter (TC 2.A.1.44) family (573 aa)
           
  0.696
RCBTB1
RCC1 and BTB domain-containing protein 1; May be involved in cell cycle regulation by chromatin remodeling; BTB domain containing (531 aa)
     
   
  0.691
TMEM74
Transmembrane protein 74; Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction; Belongs to the TMEM74 family (305 aa)
           
  0.677
SYT14
Synaptotagmin-14; May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent; Belongs to the synaptotagmin family (574 aa)
           
  0.660
RFC4
Replication factor C subunit 4; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template (363 aa)
     
   
  0.654
LPAR6
Lysophosphatidic acid receptor 6; Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture (344 aa)
           
  0.649
CDA
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis (146 aa)
         
  0.643
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]