• Version:
  • 11.0 [archived version]
STRINGSTRING
LRRC49 LRRC49 THAP5 THAP5 DNAL4 DNAL4 TP53BP1 TP53BP1 DAW1 DAW1 THAP10 THAP10 THAP4 THAP4 THAP6 THAP6 THAP7 THAP7 THAP8 THAP8 THAP9 THAP9
"THAP10" - THAP domain containing 10 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THAP10THAP domain containing 10 (257 aa)    
Predicted Functional Partners:
LRRC49
Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49 (691 aa)
     
   
  0.741
DAW1
Dynein assembly factor with WDR repeat domains 1; May play a role in axonemal outer row dynein assembly; Belongs to the WD repeat WDR69 family (415 aa)
           
  0.693
TP53BP1
TP53-binding protein 1; Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis. Plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage by promoting non-homologous end joining (NHEJ)-mediated repair of DSBs and specifically counteracting the function of the homologous recombination (HR) repair protein BRCA1. In response to DSBs, phosphorylation by ATM promotes interaction with RIF1 and dissociation from NUDT16L1/TIRR, leading to recruitment to DSBs si [...] (1977 aa)
       
      0.685
THAP8
THAP domain containing 8 (274 aa)
           
  0.669
THAP4
THAP domain containing 4 (577 aa)
           
  0.569
THAP6
THAP domain containing 6 (222 aa)
           
  0.559
THAP9
DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5’-TXXGGGX(A/T)-3’ consensus motif and mediates transposition; THAP domain containing (903 aa)
           
  0.543
THAP7
THAP domain-containing protein 7; Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors; THAP domain containing (309 aa)
           
  0.530
DNAL4
Dynein light chain 4, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity); Dyneins, axonemal (105 aa)
           
  0.529
THAP5
THAP domain-containing protein 5; Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro). May be a regulator of cell cycle- THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase; THAP domain containing (395 aa)
           
  0.525
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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