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  • 11.0 [archived version]
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SH3D19 SH3D19 RIMBP3B RIMBP3B ALS2CR11 ALS2CR11 RIMBP3C RIMBP3C TSACC TSACC EVC EVC C22orf23 C22orf23 FAM124B FAM124B VSIG8 VSIG8 C1orf204 C1orf204 TMEM200B TMEM200B
"C22orf23" - UPF0193 protein EVG1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
C22orf23UPF0193 protein EVG1; Chromosome 22 open reading frame 23 (217 aa)    
Predicted Functional Partners:
SH3D19
SH3 domain-containing protein 19; May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization (790 aa)
           
  0.673
TMEM200B
Transmembrane protein 200B (307 aa)
           
  0.618
FAM124B
Protein FAM124B; Family with sequence similarity 124 member B; Belongs to the FAM124 family (455 aa)
           
  0.600
EVC
Ellis-van Creveld syndrome protein; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Involved in endochondral growth and skeletal development (992 aa)
           
  0.591
C1orf204
Putative uncharacterized protein SNHG28; Chromosome 1 open reading frame 204 (235 aa)
           
  0.566
VSIG8
V-set and immunoglobulin domain containing 8; IgCAM CXADR-related subfamily (414 aa)
           
  0.564
TSACC
TSSK6-activating co-chaperone protein; Co-chaperone that facilitates HSP-mediated activation of TSSK6; Belongs to the TSACC family (125 aa)
           
  0.560
RIMBP3C
RIMS binding protein 3C; Belongs to the RIMBP family (1639 aa)
           
  0.557
RIMBP3B
RIMS binding protein 3B (1639 aa)
           
  0.536
ALS2CR11
C2 calcium-dependent domain-containing protein 6; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 (1820 aa)
           
  0.530
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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