• Version:
  • 11.0 [archived version]
STRINGSTRING
TRIM16L TRIM16L OR5J2 OR5J2 OR1N2 OR1N2 PAX6 PAX6 RFPL3 RFPL3 RFPL3S RFPL3S RGP1 RGP1 RFPL1 RFPL1 NARS NARS KHDC1L KHDC1L PFDN4 PFDN4
"RFPL3" - Ret finger protein-like 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFPL3Ret finger protein-like 3; (Microbial infection) Stimulates the activity of Human Immunodeficiency Virus 1/HIV-1 pre-integration complex; Ring finger proteins (317 aa)    
Predicted Functional Partners:
RFPL3S
Putative protein RFPL3S; RFPL3 antisense (107 aa)
           
  0.904
PAX6
Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes; Belongs to the paired homeobox family (436 aa)
       
 
  0.768
NARS
Asparagine--tRNA ligase, cytoplasmic; Aminoacyl tRNA synthetases, Class II (548 aa)
           
  0.757
RFPL1
Ret finger protein like 1; Ring finger proteins (317 aa)
       
 
0.693
OR1N2
Olfactory receptor 1N2; Odorant receptor; Olfactory receptors, family 1 (330 aa)
           
  0.571
KHDC1L
Putative KHDC1-like protein; KH domain containing 1 like; Belongs to the KHDC1 family (128 aa)
     
   
  0.542
OR5J2
Olfactory receptor 5J2; Odorant receptor; Olfactory receptors, family 5 (312 aa)
           
  0.530
PFDN4
Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family (134 aa)
     
      0.518
RGP1
RAB6A-GEF complex partner protein 2; The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1- RGP1 complex participates in the recycling of mannose-6-phosphate receptors (391 aa)
       
      0.513
TRIM16L
Tripartite motif-containing protein 16-like protein; Tripartite motif containing 16 like; Belongs to the TRIM/RBCC family (348 aa)
           
  0.478
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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