node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCL2L12 | NOSIP | ENSP00000482218 | ENSP00000470034 | Bcl-2-like protein 12; BCL2 like 12 | Nitric oxide synthase-interacting protein; E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity; Belongs to the NOSIP family | 0.450 |
BCL2L12 | PRR12 | ENSP00000482218 | ENSP00000394510 | Bcl-2-like protein 12; BCL2 like 12 | Proline-rich protein 12; Proline rich 12 | 0.706 |
BCL2L12 | PRRG2 | ENSP00000482218 | ENSP00000246794 | Bcl-2-like protein 12; BCL2 like 12 | Transmembrane gamma-carboxyglutamic acid protein 2; Proline rich and Gla domain containing | 0.689 |
BCL2L12 | SCAF1 | ENSP00000482218 | ENSP00000353769 | Bcl-2-like protein 12; BCL2 like 12 | Splicing factor, arginine/serine-rich 19; May function in pre-mRNA splicing | 0.707 |
C10orf12 | LCOR | ENSP00000286067 | ENSP00000360138 | Ligand-dependent corepressor; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR | Ligand-dependent corepressor; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR | 0.444 |
C10orf12 | LRRC20 | ENSP00000286067 | ENSP00000348043 | Ligand-dependent corepressor; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR | Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20 | 0.564 |
C10orf12 | PRRG2 | ENSP00000286067 | ENSP00000246794 | Ligand-dependent corepressor; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR | Transmembrane gamma-carboxyglutamic acid protein 2; Proline rich and Gla domain containing | 0.616 |
GGCX | PRRG2 | ENSP00000233838 | ENSP00000246794 | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide | Transmembrane gamma-carboxyglutamic acid protein 2; Proline rich and Gla domain containing | 0.756 |
LCOR | C10orf12 | ENSP00000360138 | ENSP00000286067 | Ligand-dependent corepressor; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR | Ligand-dependent corepressor; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR | 0.444 |
LCOR | LRRC20 | ENSP00000360138 | ENSP00000348043 | Ligand-dependent corepressor; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR | Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20 | 0.548 |
LCOR | PRRG2 | ENSP00000360138 | ENSP00000246794 | Ligand-dependent corepressor; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR | Transmembrane gamma-carboxyglutamic acid protein 2; Proline rich and Gla domain containing | 0.614 |
LRRC20 | C10orf12 | ENSP00000348043 | ENSP00000286067 | Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20 | Ligand-dependent corepressor; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR | 0.564 |
LRRC20 | LCOR | ENSP00000348043 | ENSP00000360138 | Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20 | Ligand-dependent corepressor; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR | 0.548 |
LRRC20 | PRRG2 | ENSP00000348043 | ENSP00000246794 | Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20 | Transmembrane gamma-carboxyglutamic acid protein 2; Proline rich and Gla domain containing | 0.679 |
NOSIP | BCL2L12 | ENSP00000470034 | ENSP00000482218 | Nitric oxide synthase-interacting protein; E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity; Belongs to the NOSIP family | Bcl-2-like protein 12; BCL2 like 12 | 0.450 |
NOSIP | PRR12 | ENSP00000470034 | ENSP00000394510 | Nitric oxide synthase-interacting protein; E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity; Belongs to the NOSIP family | Proline-rich protein 12; Proline rich 12 | 0.656 |
NOSIP | PRRG2 | ENSP00000470034 | ENSP00000246794 | Nitric oxide synthase-interacting protein; E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity; Belongs to the NOSIP family | Transmembrane gamma-carboxyglutamic acid protein 2; Proline rich and Gla domain containing | 0.698 |
NOSIP | RCN3 | ENSP00000470034 | ENSP00000270645 | Nitric oxide synthase-interacting protein; E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity; Belongs to the NOSIP family | Reticulocalbin-3; EF-hand domain containing; Belongs to the CREC family | 0.771 |
NOSIP | SCAF1 | ENSP00000470034 | ENSP00000353769 | Nitric oxide synthase-interacting protein; E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity; Belongs to the NOSIP family | Splicing factor, arginine/serine-rich 19; May function in pre-mRNA splicing | 0.486 |
PRR12 | BCL2L12 | ENSP00000394510 | ENSP00000482218 | Proline-rich protein 12; Proline rich 12 | Bcl-2-like protein 12; BCL2 like 12 | 0.706 |