• Version:
  • 11.0 [archived version]
STRINGSTRING
DEFB110 DEFB110 DEFB116 DEFB116 DEFB126 DEFB126 DEFB125 DEFB125 DEFB113 DEFB113 DEFB121 DEFB121 DEFB128 DEFB128 DEFB129 DEFB129 DEFB127 DEFB127 DEFB132 DEFB132 DEFB123 DEFB123
"DEFB129" - Beta-defensin 129 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB129Beta-defensin 129; Has antibacterial activity; Defensins, beta (183 aa)    
Predicted Functional Partners:
DEFB125
Beta-defensin 125; Has antibacterial activity; Defensins, beta (156 aa)
      
 
  0.982
DEFB121
Beta-defensin 121; Has antibacterial activity; Belongs to the beta-defensin family (76 aa)
      
 
  0.973
DEFB113
Beta-defensin 113; Has antibacterial activity; Defensins, beta (82 aa)
      
 
  0.972
DEFB127
Beta-defensin 127; Has antibacterial activity; Defensins, beta (99 aa)
      
 
  0.970
DEFB126
Beta-defensin 126; Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other s [...] (111 aa)
      
 
  0.966
DEFB110
Beta-defensin 110; Has antibacterial activity; Defensins, beta (67 aa)
      
 
  0.964
DEFB128
Beta-defensin 128; Has antibacterial activity; Defensins, beta (93 aa)
      
 
  0.958
DEFB132
Beta-defensin 132; Has antibacterial activity; Defensins, beta (95 aa)
      
 
  0.958
DEFB123
Beta-defensin 123; Has antibacterial activity; Belongs to the beta-defensin family (67 aa)
      
 
  0.953
DEFB116
Beta-defensin 116; Has antibacterial activity; Defensins, beta (102 aa)
      
 
  0.953
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >