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  • 11.0 [archived version]
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CCDC51 CCDC51 CLCN4 CLCN4 CPNE5 CPNE5 LRRC10B LRRC10B KCNJ4 KCNJ4 C1orf198 C1orf198 LAMP5 LAMP5 SLC32A1 SLC32A1 LAMP3 LAMP3 PLEKHA5 PLEKHA5 CBLN2 CBLN2
"LAMP5" - Lysosome-associated membrane glycoprotein 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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LAMP5Lysosome-associated membrane glycoprotein 5; Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain (280 aa)    
Predicted Functional Partners:
CCDC51
Coiled-coil domain containing 51 (411 aa)
           
  0.620
CBLN2
Cerebellin-2; May play role in synaptogenesis induction (224 aa)
     
   
  0.596
CPNE5
Copine-5; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes (By similarity). Plays a role in dendrite formation by melanocytes; Belongs to the copine family (593 aa)
     
   
  0.596
LRRC10B
Leucine-rich repeat-containing protein 10B; Leucine rich repeat containing 10B (292 aa)
     
   
  0.590
C1orf198
Uncharacterized protein C1orf198; Chromosome 1 open reading frame 198 (327 aa)
           
  0.587
KCNJ4
Inward rectifier potassium channel 4; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity); Potassium voltage-gated channel subfamily J (445 aa)
     
   
  0.566
PLEKHA5
Pleckstrin homology domain containing A5 (1282 aa)
           
  0.559
SLC32A1
Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Solute carriers (525 aa)
     
 
  0.523
CLCN4
H(+)/Cl(-) exchange transporter 4; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons; Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily (760 aa)
     
   
  0.518
LAMP3
Lysosome-associated membrane glycoprotein 3; May play a role in dendritic cell function and in adaptive immunity; CD molecules (416 aa)
           
  0.515
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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