node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTR2 | MYH1 | ENSP00000367220 | ENSP00000226207 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.409 |
ACTR2 | MYH2 | ENSP00000367220 | ENSP00000245503 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity); Myosin heavy chains | 0.930 |
ACTR2 | RHOA | ENSP00000367220 | ENSP00000400175 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Transforming protein RhoA; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated r [...] | 0.689 |
ACTR2 | TPM1 | ENSP00000367220 | ENSP00000351022 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | Tropomyosin alpha-1 chain; Tropomyosin 1; Tropomyosins | 0.617 |
MYH1 | ACTR2 | ENSP00000226207 | ENSP00000367220 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | 0.409 |
MYH1 | MYH2 | ENSP00000226207 | ENSP00000245503 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity); Myosin heavy chains | 0.958 |
MYH1 | MYL1 | ENSP00000226207 | ENSP00000307280 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin light chain 1/3, skeletal muscle isoform; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.982 |
MYH1 | MYL3 | ENSP00000226207 | ENSP00000379210 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.951 |
MYH1 | MYL5 | ENSP00000226207 | ENSP00000383023 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin light chain 5; EF-hand domain containing | 0.944 |
MYH1 | MYL6B | ENSP00000226207 | ENSP00000450385 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.948 |
MYH1 | MYL9 | ENSP00000226207 | ENSP00000279022 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing | 0.949 |
MYH1 | MYLPF | ENSP00000226207 | ENSP00000325239 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin light chain, phosphorylatable, fast skeletal muscle; EF-hand domain containing | 0.974 |
MYH1 | TPM1 | ENSP00000226207 | ENSP00000351022 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Tropomyosin alpha-1 chain; Tropomyosin 1; Tropomyosins | 0.943 |
MYH2 | ACTR2 | ENSP00000245503 | ENSP00000367220 | Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity); Myosin heavy chains | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | 0.930 |
MYH2 | MYH1 | ENSP00000245503 | ENSP00000226207 | Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity); Myosin heavy chains | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.958 |
MYH2 | MYL1 | ENSP00000245503 | ENSP00000307280 | Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity); Myosin heavy chains | Myosin light chain 1/3, skeletal muscle isoform; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.967 |
MYH2 | MYL3 | ENSP00000245503 | ENSP00000379210 | Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity); Myosin heavy chains | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.947 |
MYH2 | MYL5 | ENSP00000245503 | ENSP00000383023 | Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity); Myosin heavy chains | Myosin light chain 5; EF-hand domain containing | 0.944 |
MYH2 | MYL6B | ENSP00000245503 | ENSP00000450385 | Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity); Myosin heavy chains | Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.945 |
MYH2 | MYL9 | ENSP00000245503 | ENSP00000279022 | Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity); Myosin heavy chains | Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing | 0.938 |