SCGB1D2 protein (human) - STRING database

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SCGB1D2

Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins (90 aa)

Predicted Functional Partners:

SCGB2A2

0.978

LIPA

0.931

SCGB2A1

0.899

SCGB1D1

0.748

LIPT1

0.736

LIPF

0.720

LIPC

0.715

MUCL1

0.706

C16orf93

0.622

ALPK1

0.622

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALPK1	SCGB1D2	ENSP00000398048	ENSP00000244926	Alpha-protein kinase 1; Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	0.622
C16orf93	SCGB1D2	ENSP00000437532	ENSP00000244926	Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	0.622
LIPA	LIPC	ENSP00000337354	ENSP00000299022	Lysosomal acid lipase/cholesteryl ester hydrolase; Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor- mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation; Belongs to the AB hydrolase superfamily. Lipase family	Hepatic triacylglycerol lipase; Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin	0.710
LIPA	SCGB1D2	ENSP00000337354	ENSP00000244926	Lysosomal acid lipase/cholesteryl ester hydrolase; Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor- mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation; Belongs to the AB hydrolase superfamily. Lipase family	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	0.931
LIPC	LIPA	ENSP00000299022	ENSP00000337354	Hepatic triacylglycerol lipase; Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin	Lysosomal acid lipase/cholesteryl ester hydrolase; Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor- mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation; Belongs to the AB hydrolase superfamily. Lipase family	0.710
LIPC	LIPF	ENSP00000299022	ENSP00000377900	Hepatic triacylglycerol lipase; Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin	Lipase F, gastric type; Lipases	0.918
LIPC	SCGB1D2	ENSP00000299022	ENSP00000244926	Hepatic triacylglycerol lipase; Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	0.715
LIPF	LIPC	ENSP00000377900	ENSP00000299022	Lipase F, gastric type; Lipases	Hepatic triacylglycerol lipase; Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin	0.918
LIPF	SCGB1D2	ENSP00000377900	ENSP00000244926	Lipase F, gastric type; Lipases	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	0.720
LIPT1	SCGB1D2	ENSP00000377115	ENSP00000244926	Lipoyltransferase 1, mitochondrial; Catalyzes the transfer of the lipoyl group from lipoyl- AMP to the specific lysine residue of lipoyl domains of lipoate- dependent enzymes; Belongs to the LplA family	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	0.736
MUCL1	SCGB1D2	ENSP00000311364	ENSP00000244926	Mucin-like protein 1; May play a role as marker for the diagnosis of metastatic breast cancer	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	0.706
MUCL1	SCGB2A2	ENSP00000311364	ENSP00000227918	Mucin-like protein 1; May play a role as marker for the diagnosis of metastatic breast cancer	Mammaglobin-A; Secretoglobin family 2A member 2; Secretoglobins	0.954
SCGB1D1	SCGB1D2	ENSP00000303070	ENSP00000244926	Secretoglobin family 1D member 1; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	0.748
SCGB1D1	SCGB2A1	ENSP00000303070	ENSP00000244930	Secretoglobin family 1D member 1; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	Mammaglobin-B; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Belongs to the secretoglobin family. Lipophilin subfamily	0.811
SCGB1D1	SCGB2A2	ENSP00000303070	ENSP00000227918	Secretoglobin family 1D member 1; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	Mammaglobin-A; Secretoglobin family 2A member 2; Secretoglobins	0.846
SCGB1D2	ALPK1	ENSP00000244926	ENSP00000398048	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	Alpha-protein kinase 1; Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation	0.622
SCGB1D2	C16orf93	ENSP00000244926	ENSP00000437532	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93	0.622
SCGB1D2	LIPA	ENSP00000244926	ENSP00000337354	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	Lysosomal acid lipase/cholesteryl ester hydrolase; Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor- mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation; Belongs to the AB hydrolase superfamily. Lipase family	0.931
SCGB1D2	LIPC	ENSP00000244926	ENSP00000299022	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	Hepatic triacylglycerol lipase; Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin	0.715
SCGB1D2	LIPF	ENSP00000244926	ENSP00000377900	Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins	Lipase F, gastric type; Lipases	0.720

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