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  • 11.0 [archived version]
STRINGSTRING
GPATCH11 GPATCH11 C4orf33 C4orf33 MSL1 MSL1 BTN3A3 BTN3A3 BTN3A1 BTN3A1 GBP1 GBP1 BTN3A2 BTN3A2 IPP IPP
"BTN3A3" - Butyrophilin subfamily 3 member A3 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
BTN3A3Butyrophilin subfamily 3 member A3; Plays a role in T-cell responses in the adaptive immune response; Belongs to the immunoglobulin superfamily. BTN/MOG family (584 aa)    
Predicted Functional Partners:
BTN3A2
Butyrophilin subfamily 3 member A2; Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells; Belongs to the immunoglobulin superfamily. BTN/MOG family (334 aa)
     
 
0.847
BTN3A1
Butyrophilin subfamily 3 member A1; Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate; Butyrophilins (513 aa)
     
   
0.775
IPP
Actin-binding protein IPP; May play a role in organizing the actin cytoskeleton; BTB domain containing (584 aa)
     
   
  0.728
C4orf33
UPF0462 protein C4orf33; Chromosome 4 open reading frame 33 (199 aa)
           
  0.424
MSL1
Male-specific lethal 1 homolog; Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at ’Lys-16’ (H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at ’Lys-34’ (H2BK34Ub). This modification in turn stimulates histone H3 methylation at ’Lys-4’ (H3K4me) and ’Lys-79’ (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together fo [...] (351 aa)
           
  0.418
GPATCH11
G-patch domain containing 11 (285 aa)
           
  0.418
GBP1
Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (592 aa)
     
   
  0.409
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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