• Version:
  • 11.0 [archived version]
STRINGSTRING
LYPD4 LYPD4 LY6K LY6K TCF19 TCF19 CCHCR1 CCHCR1 RNF39 RNF39 ZNRD1 ZNRD1 MOG MOG CDSN CDSN ABCF1 ABCF1 ZNF57 ZNF57 HLA-F HLA-F
"RNF39" - RING finger protein 39 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF39RING finger protein 39; May play a role in prolonged long term-potentiation (LTP) maintenance; Ring finger proteins (420 aa)    
Predicted Functional Partners:
ZNRD1
DNA-directed RNA polymerase I subunit RPA12; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors (126 aa)
           
  0.806
TCF19
Transcription factor 19; Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression; PHD finger proteins (345 aa)
           
  0.775
HLA-F
HLA class I histocompatibility antigen, alpha chain F; Involved in the presentation of foreign antigens to the immune system; C1-set domain containing (442 aa)
           
  0.759
ZNF57
Zinc finger protein 57; May be involved in transcriptional regulation; Zinc fingers C2H2-type (555 aa)
     
 
  0.732
CCHCR1
Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation (871 aa)
       
 
  0.698
CDSN
Corneodesmosin; Important for the epidermal barrier integrity (529 aa)
     
   
  0.689
ABCF1
ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F (845 aa)
           
  0.671
MOG
Myelin-oligodendrocyte glycoprotein; Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell- cell communication; Belongs to the immunoglobulin superfamily. BTN/MOG family (252 aa)
           
  0.656
LY6K
Lymphocyte antigen 6K; Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida (By similarity). May play a role in cell growth; LY6/PLAUR domain containing (165 aa)
           
  0.634
LYPD4
LY6/PLAUR domain containing 4 (246 aa)
           
  0.632
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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