• Version:
  • 11.0 [archived version]
STRINGSTRING
HCFC2 HCFC2 TMUB2 TMUB2 RASGEF1C RASGEF1C ARL11 ARL11 EBPL EBPL KCNRG KCNRG ALG11 ALG11 SPRYD7 SPRYD7 CAB39L CAB39L DLEU7 DLEU7 DHCR7 DHCR7
"EBPL" - Emopamil-binding protein-like in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EBPLEmopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands (206 aa)    
Predicted Functional Partners:
ALG11
GDP-Man-Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily (492 aa)
 
            0.667
SPRYD7
SPRY domain containing 7 (196 aa)
           
  0.588
DLEU7
Leukemia-associated protein 7; Deleted in lymphocytic leukemia, 7 (160 aa)
           
  0.555
CAB39L
Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity) (337 aa)
           
  0.473
ARL11
ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor; Belongs to the small GTPase superfamily. Arf family (196 aa)
           
  0.473
KCNRG
Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes (272 aa)
           
  0.472
TMUB2
Transmembrane and ubiquitin like domain containing 2 (321 aa)
           
  0.469
RASGEF1C
Ras-GEF domain-containing family member 1C; Guanine nucleotide exchange factor (GEF) (466 aa)
           
  0.459
DHCR7
7-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC); Belongs to the ERG4/ERG24 family (475 aa)
     
   
  0.454
HCFC2
Host cell factor C2 (792 aa)
           
  0.454
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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