node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALG11 | EBPL | ENSP00000430236 | ENSP00000242827 | GDP-Man-Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | 0.667 |
ARL11 | CAB39L | ENSP00000282026 | ENSP00000479669 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor; Belongs to the small GTPase superfamily. Arf family | Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity) | 0.462 |
ARL11 | EBPL | ENSP00000282026 | ENSP00000242827 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor; Belongs to the small GTPase superfamily. Arf family | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | 0.473 |
ARL11 | KCNRG | ENSP00000282026 | ENSP00000324191 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor; Belongs to the small GTPase superfamily. Arf family | Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes | 0.473 |
ARL11 | SPRYD7 | ENSP00000282026 | ENSP00000354774 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor; Belongs to the small GTPase superfamily. Arf family | SPRY domain containing 7 | 0.476 |
CAB39L | ARL11 | ENSP00000479669 | ENSP00000282026 | Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity) | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor; Belongs to the small GTPase superfamily. Arf family | 0.462 |
CAB39L | EBPL | ENSP00000479669 | ENSP00000242827 | Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity) | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | 0.473 |
CAB39L | SPRYD7 | ENSP00000479669 | ENSP00000354774 | Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity) | SPRY domain containing 7 | 0.476 |
DHCR7 | EBPL | ENSP00000347717 | ENSP00000242827 | 7-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC); Belongs to the ERG4/ERG24 family | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | 0.454 |
DLEU7 | EBPL | ENSP00000420976 | ENSP00000242827 | Leukemia-associated protein 7; Deleted in lymphocytic leukemia, 7 | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | 0.555 |
DLEU7 | KCNRG | ENSP00000420976 | ENSP00000324191 | Leukemia-associated protein 7; Deleted in lymphocytic leukemia, 7 | Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes | 0.400 |
DLEU7 | SPRYD7 | ENSP00000420976 | ENSP00000354774 | Leukemia-associated protein 7; Deleted in lymphocytic leukemia, 7 | SPRY domain containing 7 | 0.472 |
EBPL | ALG11 | ENSP00000242827 | ENSP00000430236 | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | GDP-Man-Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | 0.667 |
EBPL | ARL11 | ENSP00000242827 | ENSP00000282026 | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor; Belongs to the small GTPase superfamily. Arf family | 0.473 |
EBPL | CAB39L | ENSP00000242827 | ENSP00000479669 | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity) | 0.473 |
EBPL | DHCR7 | ENSP00000242827 | ENSP00000347717 | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | 7-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC); Belongs to the ERG4/ERG24 family | 0.454 |
EBPL | DLEU7 | ENSP00000242827 | ENSP00000420976 | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | Leukemia-associated protein 7; Deleted in lymphocytic leukemia, 7 | 0.555 |
EBPL | HCFC2 | ENSP00000242827 | ENSP00000229330 | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | Host cell factor C2 | 0.454 |
EBPL | KCNRG | ENSP00000242827 | ENSP00000324191 | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes | 0.472 |
EBPL | RASGEF1C | ENSP00000242827 | ENSP00000377037 | Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands | Ras-GEF domain-containing family member 1C; Guanine nucleotide exchange factor (GEF) | 0.459 |